Design, synthesis, and modeling of novel cyclic thrombin receptor-derived peptide analogues of the Ser42-Phe-Leu-Leu-Arg46 motif sequence with fixed conformations of pharmacophoric groups: importance of a Phe/Arg/NH2 cluster for receptor activation and implications in the design of nonpeptide thrombin receptor mimetics.
Source:http://linkedlifedata.com/resource/pubmed/id/11462974
J. Med. Chem.
2001
Feb
1
44
3
328-39
