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pubmed-article:11422326pubmed:dateCreated2001-6-25lld:pubmed
pubmed-article:11422326pubmed:abstractTextTwo subtypes of temporal lobe epilepsy (TLE) can be defined through clinical observations and analysis of hippocampal tissue resected during surgical procedures for intractable TLE: (a) mesial temporal sclerosis (MTS), which is characterized by extensive changes to the hippocampus and good surgical outcome; and (b) paradoxical temporal lobe epilepsy (PTLE), which is characterized by minimal cell loss and comparatively poorer surgical outcome. Patients in both subtypes have seizures that appear to begin in the medial temporal lobe, but documented differences in substrate and outcome between these subtypes has defined a need to distinguish MTS and PTLE patients before surgery. This report describes a retrospective study to investigate the feasibility of doing so during intracranial monitoring.lld:pubmed
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pubmed-article:11422326pubmed:authorpubmed-author:SpencerS SSSlld:pubmed
pubmed-article:11422326pubmed:authorpubmed-author:DuckrowR BRBlld:pubmed
pubmed-article:11422326pubmed:authorpubmed-author:ZaveriH PHPlld:pubmed
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pubmed-article:11422326pubmed:dateRevised2004-11-17lld:pubmed
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pubmed-article:11422326pubmed:year2001lld:pubmed
pubmed-article:11422326pubmed:articleTitleDistinguishing subtypes of temporal lobe epilepsy with background hippocampal activity.lld:pubmed
pubmed-article:11422326pubmed:affiliationDepartment of Neurology, Yale University School of Medicine, New Haven, CT 06520-8018, U.S.A. Hitten.Zaveri@yale.edulld:pubmed
pubmed-article:11422326pubmed:publicationTypeJournal Articlelld:pubmed