To study the effect of weight loss and subsequent weight maintenance or weight regain on the activities of FVII and plasminogen activator inhibitor 1 (PAI-1) and the concentration of fibrinogen over 12 months in obese women consuming a hypoenergetic, low-fat diet with or without orlistat. In addition, the relation between the changes of the activities of PAI-1 and FVII with the changes of other cardiovascular risk factors were examined.
Department of Clinical Nutrition, University of Kuopio, Kuopio, Finland, and Obesity Research Unit, Helsinki University Central Hospital, Helsinki, Finland. paivi.risanen@hus.fi
