Linked Life Data

11407996

Source:http://linkedlifedata.com/resource/pubmed/id/11407996

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pubmed-article:11407996pubmed:abstractTextThe human NOTCH4 gene is a candidate gene for schizophrenia due to its chromosomal location and neurobiological roles. In a British linkage study, NOTCH4 gene polymorphisms were highly associated with schizophrenia. In a Japanese case-control association study, however, these polymorphisms did not show significant associations with schizophrenia. We conducted a case-control study with Japanese subjects to explore an association between the triplet repeat polymorphism in the NOTCH4 gene and schizophrenia, including subtypes of schizophrenia, longitudinal disease course characteristics, and a positive family history for psychoses.lld:pubmed
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pubmed-article:11407996pubmed:dateRevised2009-11-18lld:pubmed
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pubmed-article:11407996pubmed:articleTitleThe (CTG)n polymorphism in the NOTCH4 gene is not associated with schizophrenia in Japanese individuals.lld:pubmed
pubmed-article:11407996pubmed:affiliationDepartment of Psychiatry, Institute of Clinical Medicine, University of Tsukuba, Tsukuba City, Ibaraki, Japan. zc6k-imi@asahi-net.or.jplld:pubmed
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