| pubmed-article:11403224 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:11403224 | lifeskim:mentions | umls-concept:C0004096 | lld:lifeskim |
| pubmed-article:11403224 | lifeskim:mentions | umls-concept:C1522424 | lld:lifeskim |
| pubmed-article:11403224 | lifeskim:mentions | umls-concept:C0026336 | lld:lifeskim |
| pubmed-article:11403224 | lifeskim:mentions | umls-concept:C0021467 | lld:lifeskim |
| pubmed-article:11403224 | lifeskim:mentions | umls-concept:C1704632 | lld:lifeskim |
| pubmed-article:11403224 | lifeskim:mentions | umls-concept:C0871261 | lld:lifeskim |
| pubmed-article:11403224 | lifeskim:mentions | umls-concept:C0678812 | lld:lifeskim |
| pubmed-article:11403224 | lifeskim:mentions | umls-concept:C0162326 | lld:lifeskim |
| pubmed-article:11403224 | lifeskim:mentions | umls-concept:C2911692 | lld:lifeskim |
| pubmed-article:11403224 | lifeskim:mentions | umls-concept:C1706817 | lld:lifeskim |
| pubmed-article:11403224 | lifeskim:mentions | umls-concept:C0021469 | lld:lifeskim |
| pubmed-article:11403224 | lifeskim:mentions | umls-concept:C0086597 | lld:lifeskim |
| pubmed-article:11403224 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:11403224 | pubmed:dateCreated | 2001-6-13 | lld:pubmed |
| pubmed-article:11403224 | pubmed:abstractText | This study investigated whether immunostimulatory DNA sequences (ISS) induce a transient or sustained inhibition of Th2 responses to inhaled antigen. We sensitized mice with subcutaneous injections to develop a Th2 response to ovalbumin (ova) and then administered a dose of ISS prior to ova inhalation challenge. Mice were then rechallenged with ova by inhalation a second time at varying time points after the first ova inhalation (1 to 8 weeks later) to determine whether the ISS dose administered prior to the first ova inhalation protected against a subsequent second ova inhalation challenge. A single dose of ISS inhibited the Th2 response to the first inhalation of ova antigen, as well as 4 weeks later to the second inhalation of ova. However, ISS did not inhibit a Th2 response to the second inhalation of ova 8 weeks later. The reversible inhibition of Th2 responses at 8 weeks suggests the need for repeated ISS administration at monthly intervals. | lld:pubmed |
| pubmed-article:11403224 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11403224 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11403224 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11403224 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11403224 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11403224 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11403224 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:11403224 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11403224 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11403224 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11403224 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11403224 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11403224 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11403224 | pubmed:month | May | lld:pubmed |
| pubmed-article:11403224 | pubmed:issn | 0271-9142 | lld:pubmed |
| pubmed-article:11403224 | pubmed:author | pubmed-author:MillerMM | lld:pubmed |
| pubmed-article:11403224 | pubmed:author | pubmed-author:HayashiTT | lld:pubmed |
| pubmed-article:11403224 | pubmed:author | pubmed-author:RaoNN | lld:pubmed |
| pubmed-article:11403224 | pubmed:author | pubmed-author:RomanMM | lld:pubmed |
| pubmed-article:11403224 | pubmed:author | pubmed-author:DayJ KJK | lld:pubmed |
| pubmed-article:11403224 | pubmed:author | pubmed-author:HyashiTT | lld:pubmed |
| pubmed-article:11403224 | pubmed:author | pubmed-author:BroideD HDH | lld:pubmed |
| pubmed-article:11403224 | pubmed:author | pubmed-author:NayakMM | lld:pubmed |
| pubmed-article:11403224 | pubmed:author | pubmed-author:ZubeldiaJJ | lld:pubmed |
| pubmed-article:11403224 | pubmed:author | pubmed-author:CastanedaDD | lld:pubmed |
| pubmed-article:11403224 | pubmed:author | pubmed-author:StachnickGG | lld:pubmed |
| pubmed-article:11403224 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11403224 | pubmed:volume | 21 | lld:pubmed |
| pubmed-article:11403224 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11403224 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11403224 | pubmed:pagination | 175-82 | lld:pubmed |
| pubmed-article:11403224 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:11403224 | pubmed:meshHeading | pubmed-meshheading:11403224... | lld:pubmed |
| pubmed-article:11403224 | pubmed:meshHeading | pubmed-meshheading:11403224... | lld:pubmed |
| pubmed-article:11403224 | pubmed:meshHeading | pubmed-meshheading:11403224... | lld:pubmed |
| pubmed-article:11403224 | pubmed:meshHeading | pubmed-meshheading:11403224... | lld:pubmed |
| pubmed-article:11403224 | pubmed:meshHeading | pubmed-meshheading:11403224... | lld:pubmed |
| pubmed-article:11403224 | pubmed:meshHeading | pubmed-meshheading:11403224... | lld:pubmed |
| pubmed-article:11403224 | pubmed:meshHeading | pubmed-meshheading:11403224... | lld:pubmed |
| pubmed-article:11403224 | pubmed:meshHeading | pubmed-meshheading:11403224... | lld:pubmed |
| pubmed-article:11403224 | pubmed:meshHeading | pubmed-meshheading:11403224... | lld:pubmed |
| pubmed-article:11403224 | pubmed:meshHeading | pubmed-meshheading:11403224... | lld:pubmed |
| pubmed-article:11403224 | pubmed:meshHeading | pubmed-meshheading:11403224... | lld:pubmed |
| pubmed-article:11403224 | pubmed:meshHeading | pubmed-meshheading:11403224... | lld:pubmed |
| pubmed-article:11403224 | pubmed:meshHeading | pubmed-meshheading:11403224... | lld:pubmed |
| pubmed-article:11403224 | pubmed:meshHeading | pubmed-meshheading:11403224... | lld:pubmed |
| pubmed-article:11403224 | pubmed:meshHeading | pubmed-meshheading:11403224... | lld:pubmed |
| pubmed-article:11403224 | pubmed:meshHeading | pubmed-meshheading:11403224... | lld:pubmed |
| pubmed-article:11403224 | pubmed:meshHeading | pubmed-meshheading:11403224... | lld:pubmed |
| pubmed-article:11403224 | pubmed:year | 2001 | lld:pubmed |
| pubmed-article:11403224 | pubmed:articleTitle | Systemic administration of immunostimulatory DNA sequences mediates reversible inhibition of Th2 responses in a mouse model of asthma. | lld:pubmed |
| pubmed-article:11403224 | pubmed:affiliation | Department of Medicine, University of California, San Diego, La Jolla 92093, USA. dbroide@ucsd.edu | lld:pubmed |
| pubmed-article:11403224 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:11403224 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11403224 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11403224 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11403224 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11403224 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11403224 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11403224 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11403224 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11403224 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11403224 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11403224 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11403224 | lld:pubmed |
