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pubmed-article:11393423pubmed:abstractTextThe prognosis of Mycobacterium avium complex (MAC) infection has been improved by new macrolides-containing regimens and the use of highly active antiretroviral therapy (HAART) in the treatment of acquired immunodeficiency syndrome (AIDS). We report on two AIDS cases with long lasting bacteremia due to MAC under this regimen. Both patients experienced problems due to side effects from the anti-MAC regimen and from an immune-reconstitution syndrome related to HAART. MAC infection persisted despite treatment, however, no anti-MAC drug-resistant isolates emerged throughout the clinical course in either case. These cases demonstrate that therapy for disseminated MAC infection is sometimes difficult even with HAART and macrolides-containing regimens.lld:pubmed
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pubmed-article:11393423pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:11393423pubmed:year2001lld:pubmed
pubmed-article:11393423pubmed:articleTitleTwo cases of long lasting bacteremia due to Mycobacterium avium complex despite new macrolides-containing regimens in patients with acquired immunodeficiency syndrome.lld:pubmed
pubmed-article:11393423pubmed:affiliationAIDS Clinical Center, International Medical Center of Japan, Tokyo.lld:pubmed
pubmed-article:11393423pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:11393423pubmed:publicationTypeCase Reportslld:pubmed
pubmed-article:11393423pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed