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pubmed-article:11343904pubmed:abstractTextLoss of the p53 tumor suppressor pathway contributes to the development of most human cancers. p53 is a nuclear protein that functions as a regulator of transcription. Significant advances have been made recently in our understanding of how p53 function is regulated and the mechanisms by which p53 mediates its effects.lld:pubmed
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pubmed-article:11343904pubmed:articleTitleRegulation and function of the p53 tumor suppressor protein.lld:pubmed
pubmed-article:11343904pubmed:affiliationRegulation of Cell Growth Laboratory, Building 560, Room 22-96, National Cancer Institute at Frederick, Frederick, MD 21702, USA.lld:pubmed
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