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pubmed-article:11324955pubmed:dateCreated2001-4-27lld:pubmed
pubmed-article:11324955pubmed:abstractTextA 32-channel time-resolved optical imaging instrument has been developed principally to study functional parameters of the new-born infant brain. As a prelude to studies on infants, the device and image reconstruction methodology have been evaluated on the adult human forearm. Cross-sectional images were generated using time-resolved measurements of transmitted light at two wavelengths. All data were acquired using a fully automated computer-controlled protocol. Images representing the internal scattering and absorbing properties of the arm are presented, as well as images that reveal physiological changes during a simple finger flexion exercise. The results presented in this paper represent the first simultaneous tomographic reconstruction of the internal scattering and absorbing properties of a clinical subject using purely temporal data, with additional co-registered difference images showing repeatable absorption changes at two wavelengths in response to exercise.lld:pubmed
pubmed-article:11324955pubmed:languageenglld:pubmed
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pubmed-article:11324955pubmed:authorpubmed-author:SchweigerMMlld:pubmed
pubmed-article:11324955pubmed:authorpubmed-author:SchmidtF EFElld:pubmed
pubmed-article:11324955pubmed:authorpubmed-author:DelpyD TDTlld:pubmed
pubmed-article:11324955pubmed:authorpubmed-author:ArridgeS RSRlld:pubmed
pubmed-article:11324955pubmed:authorpubmed-author:HebdenJ CJClld:pubmed
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pubmed-article:11324955pubmed:authorpubmed-author:HillmanE MEMlld:pubmed
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pubmed-article:11324955pubmed:volume46lld:pubmed
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pubmed-article:11324955pubmed:pagination1117-30lld:pubmed
pubmed-article:11324955pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:11324955pubmed:year2001lld:pubmed
pubmed-article:11324955pubmed:articleTitleTime resolved optical tomography of the human forearm.lld:pubmed
pubmed-article:11324955pubmed:affiliationDepartment of Medical Physics and Bioengineering, University College London, UK.lld:pubmed
pubmed-article:11324955pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:11324955pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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