| pubmed-article:11321484 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:11321484 | lifeskim:mentions | umls-concept:C0003402 | lld:lifeskim |
| pubmed-article:11321484 | lifeskim:mentions | umls-concept:C1524119 | lld:lifeskim |
| pubmed-article:11321484 | lifeskim:mentions | umls-concept:C1882598 | lld:lifeskim |
| pubmed-article:11321484 | lifeskim:mentions | umls-concept:C0023789 | lld:lifeskim |
| pubmed-article:11321484 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:11321484 | lifeskim:mentions | umls-concept:C1419926 | lld:lifeskim |
| pubmed-article:11321484 | lifeskim:mentions | umls-concept:C0023775 | lld:lifeskim |
| pubmed-article:11321484 | lifeskim:mentions | umls-concept:C1521827 | lld:lifeskim |
| pubmed-article:11321484 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:11321484 | pubmed:dateCreated | 2001-4-25 | lld:pubmed |
| pubmed-article:11321484 | pubmed:abstractText | The levels of lipofuscin and lipid peroxidation reflect the degree of free radical-induced oxidative damage in the brain. We examined the effects of CDA-II, a preparation of human urine, on lipofuscin and lipid peroxidation in the brain of young (3.5 months) and middle-aged rats (17 months). The rats were given CDA-II orally at dosages of 0.3 or 1.0 g/kg daily for 8 weeks. CDA-II significantly suppressed the contents of lipofuscin and lipid peroxidation in both young and middle-aged rats. CDA-II also elevated the activity of superoxide dismutase, and the amounts of glutathione and ascorbic acid in the middle-aged rats, but not in the young ones. Our results suggest that the protection against oxidative damage by CDA-II in the young rat brain may be due to its scavenging activity against free radicals. In the middle-aged rats, in addition to the scavenging activity, the levels of endogenous antioxidants were also enhanced by the CDA-II treatment. | lld:pubmed |
| pubmed-article:11321484 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11321484 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11321484 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:11321484 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11321484 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11321484 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11321484 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11321484 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11321484 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11321484 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11321484 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11321484 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11321484 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11321484 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11321484 | pubmed:issn | 0192-415X | lld:pubmed |
| pubmed-article:11321484 | pubmed:author | pubmed-author:LiauM CMC | lld:pubmed |
| pubmed-article:11321484 | pubmed:author | pubmed-author:CHUH AHA | lld:pubmed |
| pubmed-article:11321484 | pubmed:author | pubmed-author:TURM MMM | lld:pubmed |
| pubmed-article:11321484 | pubmed:author | pubmed-author:XueFF | lld:pubmed |
| pubmed-article:11321484 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11321484 | pubmed:volume | 29 | lld:pubmed |
| pubmed-article:11321484 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11321484 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11321484 | pubmed:pagination | 91-9 | lld:pubmed |
| pubmed-article:11321484 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:11321484 | pubmed:meshHeading | pubmed-meshheading:11321484... | lld:pubmed |
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| pubmed-article:11321484 | pubmed:meshHeading | pubmed-meshheading:11321484... | lld:pubmed |
| pubmed-article:11321484 | pubmed:year | 2001 | lld:pubmed |
| pubmed-article:11321484 | pubmed:articleTitle | Effect of CDA-II, urinary preparation, on lipofuscin, lipid peroxidation and antioxidant systems in young and middle-aged rat brain. | lld:pubmed |
| pubmed-article:11321484 | pubmed:affiliation | Department of Pharmacology, China Medical College, Taichung, Taiwan. | lld:pubmed |
| pubmed-article:11321484 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:11321484 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
