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pubmed-article:11316245pubmed:abstractTextIt has been suggested that angiotensin II (Ang II) promotes hypertrophy and hyperplasia of mesangial cells. Nonmuscle myosin heavy chain-B (NMHC-B) and alpha-smooth muscle (SM) actin are considered to be molecular markers for phenotypic change ofproliferative mesangial cells. One of the clinical characteristics in Gitelman's syndrome (GS) is the elevation of plasma Ang II. However, little is known about the relation between Ang II and phenotypic change of mesangial cells in patients with GS. In this report, we examined the expression of NMHC-B and alpha-SM actin in mesangial cells of two GS patients.lld:pubmed
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pubmed-article:11316245pubmed:articleTitleHeterogeneous expression of nonmuscle myosin heavy chain-B in mesangial cells of patients with Gitelman's syndrome.lld:pubmed
pubmed-article:11316245pubmed:affiliationThe 2nd Department of Internal Medicine, Yamaguchi University School of Medicine, Ube, Japan.lld:pubmed
pubmed-article:11316245pubmed:publicationTypeJournal Articlelld:pubmed