The 3'-->5' exonuclease of DNA polymerase delta can substitute for the 5' flap endonuclease Rad27/Fen1 in processing Okazaki fragments and preventing genome instability.

Source:http://linkedlifedata.com/resource/pubmed/id/11309502

Proc. Natl. Acad. Sci. U.S.A. 2001 Apr 24 98 9 5122-7

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11309502