| pubmed-article:11294368 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:11294368 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:11294368 | lifeskim:mentions | umls-concept:C0012091 | lld:lifeskim |
| pubmed-article:11294368 | lifeskim:mentions | umls-concept:C1332829 | lld:lifeskim |
| pubmed-article:11294368 | lifeskim:mentions | umls-concept:C0182400 | lld:lifeskim |
| pubmed-article:11294368 | pubmed:issue | 11 | lld:pubmed |
| pubmed-article:11294368 | pubmed:dateCreated | 2001-4-10 | lld:pubmed |
| pubmed-article:11294368 | pubmed:abstractText | Besides the low therapeutic index drug tolbutamide, there is no validated in vivo probe to assess the genetically determined CYP2C9 activity in humans. The in vitro CYP2C9-specific substrate diclofenac might be a valuable, well-tolerated probe candidate. In order to validate diclofenac as an in vivo CYP2C9 probe, we planned to show that urinary 4'-hydroxydiclofenac/diclofenac metabolic ratio (MR) would correlate to the apparent partial metabolic clearance of diclofenac into 4'-hydroxydiclofenac (Clmet). | lld:pubmed |
| pubmed-article:11294368 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11294368 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11294368 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:11294368 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:11294368 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11294368 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11294368 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11294368 | pubmed:issn | 0031-6970 | lld:pubmed |
| pubmed-article:11294368 | pubmed:author | pubmed-author:JaillonPP | lld:pubmed |
| pubmed-article:11294368 | pubmed:author | pubmed-author:Funck-Brentan... | lld:pubmed |
| pubmed-article:11294368 | pubmed:author | pubmed-author:BecquemontLL | lld:pubmed |
| pubmed-article:11294368 | pubmed:author | pubmed-author:BeauneP HPH | lld:pubmed |
| pubmed-article:11294368 | pubmed:author | pubmed-author:PoirierJ MJM | lld:pubmed |
| pubmed-article:11294368 | pubmed:author | pubmed-author:LoriotM AMA | lld:pubmed |
| pubmed-article:11294368 | pubmed:author | pubmed-author:MorinSS | lld:pubmed |
| pubmed-article:11294368 | pubmed:author | pubmed-author:TennezeLL | lld:pubmed |
| pubmed-article:11294368 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11294368 | pubmed:volume | 56 | lld:pubmed |
| pubmed-article:11294368 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11294368 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11294368 | pubmed:pagination | 793-7 | lld:pubmed |
| pubmed-article:11294368 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:11294368 | pubmed:meshHeading | pubmed-meshheading:11294368... | lld:pubmed |
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| pubmed-article:11294368 | pubmed:meshHeading | pubmed-meshheading:11294368... | lld:pubmed |
| pubmed-article:11294368 | pubmed:meshHeading | pubmed-meshheading:11294368... | lld:pubmed |
| pubmed-article:11294368 | pubmed:meshHeading | pubmed-meshheading:11294368... | lld:pubmed |
| pubmed-article:11294368 | pubmed:meshHeading | pubmed-meshheading:11294368... | lld:pubmed |
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| pubmed-article:11294368 | pubmed:meshHeading | pubmed-meshheading:11294368... | lld:pubmed |
| pubmed-article:11294368 | pubmed:meshHeading | pubmed-meshheading:11294368... | lld:pubmed |
| pubmed-article:11294368 | pubmed:articleTitle | Is diclofenac a valuable CYP2C9 probe in humans? | lld:pubmed |
| pubmed-article:11294368 | pubmed:affiliation | Clinical Pharmacology Unit, Saint Antoine University Hospital School of Medicine, Paris, France. | lld:pubmed |
| pubmed-article:11294368 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:11294368 | pubmed:publicationType | Clinical Trial | lld:pubmed |
| pubmed-article:11294368 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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