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pubmed-article:11277962pubmed:abstractTextChronic idiopathic urticaria (CIU) is the most common type of chronic urticaria, and pruritus is the most prominent symptom. Antihistamines are the first-line treatment for CIU. Sedation and anticholinergic adverse effects are often experienced with the first-generation antihistamines and there is a risk of cardiovascular adverse effects and drug interactions with some second-generation agents. Hence, new treatment options are needed. Desloratadine is a new, potent, nonsedating antihistamine that has an excellent cardiovascular safety profile.lld:pubmed
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pubmed-article:11277962pubmed:articleTitleOnce-daily desloratadine improves the signs and symptoms of chronic idiopathic urticaria: a randomized, double-blind, placebo-controlled study.lld:pubmed
pubmed-article:11277962pubmed:affiliationKlinik und Poliklinik fur Dermatologie und Allergologie am Biederstein, Technische Universität München, München, Germany.lld:pubmed
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