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pubmed-article:11239675pubmed:dateCreated2001-3-12lld:pubmed
pubmed-article:11239675pubmed:abstractTextLittle is known about frustration-induced changes in stress physiology in humans and nonhuman primates. Here we assess in two experiments with squirrel monkeys plasma levels of pituitary-adrenal stress hormones in conditions designed to provoke frustrative nonreward. In the first experiment 18 prepubertal monkeys were trained to feed from one of eight sites, and then tested without food at any of the sites. These monkeys responded with significant increases in cortisol and adrenocorticotropic hormone (ACTH). In the second experiment 18 adult monkeys were trained to feed from one of eight sites, and then tested after food was moved to a different foraging site. Nine monkeys found food at the relocated site, discontinued foraging at the previously baited site, and responded with decreases in cortisol. The other nine monkeys failed to find the relocated site, initially increased their visits to the previously baited site, and responded with elevations in cortisol and ACTH. In keeping with comparable findings in rats, our observations indicate that frustrative nonreward elicits ACTH-stimulated secretion of cortisol in primates.lld:pubmed
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pubmed-article:11239675pubmed:authorpubmed-author:LevineSSlld:pubmed
pubmed-article:11239675pubmed:authorpubmed-author:DahlC ICIlld:pubmed
pubmed-article:11239675pubmed:authorpubmed-author:LyonsD MDMlld:pubmed
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pubmed-article:11239675pubmed:pagination559-63lld:pubmed
pubmed-article:11239675pubmed:dateRevised2007-11-14lld:pubmed
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pubmed-article:11239675pubmed:articleTitleFrustrative nonreward and pituitary-adrenal activity in squirrel monkeys.lld:pubmed
pubmed-article:11239675pubmed:affiliationDepartment of Psychiatry and Behavioral Science, Stanford University School of Medicine, MSLS Room P111, Stanford, CA 94305-5485, USA. dmlyons@stanford.edulld:pubmed
pubmed-article:11239675pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:11239675pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
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