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pubmed-article:11205265pubmed:abstractTextThe cycle regulatory protein p27, an inhibitor of cyclin-dependent kinase (CDK), has been attributed a role in resistance to cancer chemotherapy. However, the predictive value of p27 for chemosensitivity of breast cancer is still unclear. We therefore analyzed the in vitro chemosensitivity to a series of anticancer agents in fresh breast cancer specimens and correlated it with the respective expression levels of p27.lld:pubmed
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pubmed-article:11205265pubmed:articleTitleOverexpression of p27 protein in human breast cancer correlates with in vitro resistance to doxorubicin and mitomycin C.lld:pubmed
pubmed-article:11205265pubmed:affiliationDepartment of Surgery, Affiliated Kihoku Hospital. yang-qf@mail.wakavama-med.ac.jplld:pubmed
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