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pubmed-article:11194057rdf:typepubmed:Citationlld:pubmed
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pubmed-article:11194057pubmed:dateCreated2001-2-2lld:pubmed
pubmed-article:11194057pubmed:abstractTextThe use of heparin-bonded cardiopulmonary bypass circuits (HBCs) with reduced anticoagulation protocol during cardiac surgery attenuates some of the adverse pathophysiologic responses to cardiopulmonary bypass (CPB). The strategies of how to maximize improvements in clinical outcomes using this technique are still debated. This article describes in detail a comprehensive approach to strategies developed at Boston Medical Center and the West Roxbury Veteran Affairs Medical Center in over 4000 cases in which HBC with a reduced anticoagulation protocol is used routinely. Important elements of this technique include elimination of cardiotomy reservoir during coronary artery bypass graft surgery (CABG), autologous blood priming, normothermic CPB, and precise heparin and protamine titration. Adaptation and variation in this technique to specific clinical situations is also highlighted.lld:pubmed
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pubmed-article:11194057pubmed:issn0022-1058lld:pubmed
pubmed-article:11194057pubmed:authorpubmed-author:KhuriS FSFlld:pubmed
pubmed-article:11194057pubmed:authorpubmed-author:SheminR JRJlld:pubmed
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pubmed-article:11194057pubmed:authorpubmed-author:O'GaraP JPJlld:pubmed
pubmed-article:11194057pubmed:authorpubmed-author:LillyK JKJlld:pubmed
pubmed-article:11194057pubmed:authorpubmed-author:CrowleyR FRFlld:pubmed
pubmed-article:11194057pubmed:authorpubmed-author:ReardonD LDLlld:pubmed
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pubmed-article:11194057pubmed:volume32lld:pubmed
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pubmed-article:11194057pubmed:pagination207-13lld:pubmed
pubmed-article:11194057pubmed:dateRevised2004-11-17lld:pubmed
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pubmed-article:11194057pubmed:year2000lld:pubmed
pubmed-article:11194057pubmed:articleTitleTechnique for routine use of heparin bonded circuits with a reduced anticoagulation protocol.lld:pubmed
pubmed-article:11194057pubmed:affiliationDepartment of Cardiothoracic Surgery, Boston Medical Center and West Roxbury Veteran Affairs Medical Center, Boston University School of Medicine, Harvard Medical School, Boston, Massachusetts, USA. Paul.Ogara@bmc.orglld:pubmed
pubmed-article:11194057pubmed:publicationTypeJournal Articlelld:pubmed