The lack of specific markers for the phenotyping of circulating neoplastic T cells in Sézary syndrome (SS) patients makes it difficult both to ascertain the presence of clonal cells and to quantify the tumour burden in the peripheral blood. In previous reports we showed that the lack of CD26 (dipeptidyl-aminopeptidase IV) is a characteristic feature of circulating Sézary cells (SC).
Department of Medical and Surgical Specialities, First Dermatologic Clinic, University of Turin, Via Cherasco 23, 10126 Torino, Italy. bernengo@ddmc.unito.it