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pubmed-article:11156880pubmed:abstractTextSustained shortening of the atrial effective refractory period (AERP), probably due to reduction in the L-type calcium current, is a major factor in the initiation and maintenance of atrial fibrillation (AF). We investigated underlying molecular changes by studying the relation between gene expression of the L-type calcium channel and potassium channels and AERP in patients with AF.lld:pubmed
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pubmed-article:11156880pubmed:articleTitleIon channel remodeling is related to intraoperative atrial effective refractory periods in patients with paroxysmal and persistent atrial fibrillation.lld:pubmed
pubmed-article:11156880pubmed:affiliationDepartment of Cardiology, Thoraxcenter University Hospital Groningen, The Netherlands. B.J.J.M.Brundel@med.rug.nllld:pubmed
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