| pubmed-article:11150502 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:11150502 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:11150502 | lifeskim:mentions | umls-concept:C1421507 | lld:lifeskim |
| pubmed-article:11150502 | lifeskim:mentions | umls-concept:C0225336 | lld:lifeskim |
| pubmed-article:11150502 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:11150502 | lifeskim:mentions | umls-concept:C1709059 | lld:lifeskim |
| pubmed-article:11150502 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:11150502 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:11150502 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:11150502 | pubmed:dateCreated | 2001-2-8 | lld:pubmed |
| pubmed-article:11150502 | pubmed:abstractText | WHSC2, a novel gene recently isolated within the critical region of Wolf-Hirschhorn syndrome, is expressed in endothelial cells. WHSC2 is downregulated by HIV-1 Tat, whereas it is not modulated by angiogenic and pro-differentiative molecules. WHSC2 encodes a basic polypeptide of 528 amino acids. The in vitro translated protein shows a molecular weight of 57 kDa. WHSC2 has two nuclear translocation sequences which actively mediate its transport to the nucleus, as shown in whsc2-GFP-transfected NIH-3T3. We also found a helix-loop-helix (HLH) motif in region 130-185. Since members of the HLH family control differentiation and cell cycle progression, we hypothesize that WHSC2 may function as a transcriptional repressor. | lld:pubmed |
| pubmed-article:11150502 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11150502 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11150502 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:11150502 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11150502 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11150502 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11150502 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11150502 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11150502 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11150502 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11150502 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11150502 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11150502 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11150502 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11150502 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11150502 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11150502 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11150502 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11150502 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11150502 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:11150502 | pubmed:issn | 0014-5793 | lld:pubmed |
| pubmed-article:11150502 | pubmed:author | pubmed-author:MariottiMM | lld:pubmed |
| pubmed-article:11150502 | pubmed:author | pubmed-author:ManganiniMM | lld:pubmed |
| pubmed-article:11150502 | pubmed:author | pubmed-author:MaierJ AJA | lld:pubmed |
| pubmed-article:11150502 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11150502 | pubmed:day | 29 | lld:pubmed |
| pubmed-article:11150502 | pubmed:volume | 487 | lld:pubmed |
| pubmed-article:11150502 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11150502 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11150502 | pubmed:pagination | 166-70 | lld:pubmed |
| pubmed-article:11150502 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
| pubmed-article:11150502 | pubmed:meshHeading | pubmed-meshheading:11150502... | lld:pubmed |
| pubmed-article:11150502 | pubmed:meshHeading | pubmed-meshheading:11150502... | lld:pubmed |
| pubmed-article:11150502 | pubmed:meshHeading | pubmed-meshheading:11150502... | lld:pubmed |
| pubmed-article:11150502 | pubmed:meshHeading | pubmed-meshheading:11150502... | lld:pubmed |
| pubmed-article:11150502 | pubmed:meshHeading | pubmed-meshheading:11150502... | lld:pubmed |
| pubmed-article:11150502 | pubmed:meshHeading | pubmed-meshheading:11150502... | lld:pubmed |
| pubmed-article:11150502 | pubmed:meshHeading | pubmed-meshheading:11150502... | lld:pubmed |
| pubmed-article:11150502 | pubmed:meshHeading | pubmed-meshheading:11150502... | lld:pubmed |
| pubmed-article:11150502 | pubmed:meshHeading | pubmed-meshheading:11150502... | lld:pubmed |
| pubmed-article:11150502 | pubmed:meshHeading | pubmed-meshheading:11150502... | lld:pubmed |
| pubmed-article:11150502 | pubmed:meshHeading | pubmed-meshheading:11150502... | lld:pubmed |
| pubmed-article:11150502 | pubmed:meshHeading | pubmed-meshheading:11150502... | lld:pubmed |
| pubmed-article:11150502 | pubmed:meshHeading | pubmed-meshheading:11150502... | lld:pubmed |
| pubmed-article:11150502 | pubmed:meshHeading | pubmed-meshheading:11150502... | lld:pubmed |
| pubmed-article:11150502 | pubmed:meshHeading | pubmed-meshheading:11150502... | lld:pubmed |
| pubmed-article:11150502 | pubmed:meshHeading | pubmed-meshheading:11150502... | lld:pubmed |
| pubmed-article:11150502 | pubmed:meshHeading | pubmed-meshheading:11150502... | lld:pubmed |
| pubmed-article:11150502 | pubmed:meshHeading | pubmed-meshheading:11150502... | lld:pubmed |
| pubmed-article:11150502 | pubmed:meshHeading | pubmed-meshheading:11150502... | lld:pubmed |
| pubmed-article:11150502 | pubmed:meshHeading | pubmed-meshheading:11150502... | lld:pubmed |
| pubmed-article:11150502 | pubmed:meshHeading | pubmed-meshheading:11150502... | lld:pubmed |
| pubmed-article:11150502 | pubmed:meshHeading | pubmed-meshheading:11150502... | lld:pubmed |
| pubmed-article:11150502 | pubmed:meshHeading | pubmed-meshheading:11150502... | lld:pubmed |
| pubmed-article:11150502 | pubmed:meshHeading | pubmed-meshheading:11150502... | lld:pubmed |
| pubmed-article:11150502 | pubmed:meshHeading | pubmed-meshheading:11150502... | lld:pubmed |
| pubmed-article:11150502 | pubmed:meshHeading | pubmed-meshheading:11150502... | lld:pubmed |
| pubmed-article:11150502 | pubmed:meshHeading | pubmed-meshheading:11150502... | lld:pubmed |
| pubmed-article:11150502 | pubmed:meshHeading | pubmed-meshheading:11150502... | lld:pubmed |
| pubmed-article:11150502 | pubmed:meshHeading | pubmed-meshheading:11150502... | lld:pubmed |
| pubmed-article:11150502 | pubmed:meshHeading | pubmed-meshheading:11150502... | lld:pubmed |
| pubmed-article:11150502 | pubmed:meshHeading | pubmed-meshheading:11150502... | lld:pubmed |
| pubmed-article:11150502 | pubmed:meshHeading | pubmed-meshheading:11150502... | lld:pubmed |
| pubmed-article:11150502 | pubmed:meshHeading | pubmed-meshheading:11150502... | lld:pubmed |
| pubmed-article:11150502 | pubmed:meshHeading | pubmed-meshheading:11150502... | lld:pubmed |
| pubmed-article:11150502 | pubmed:meshHeading | pubmed-meshheading:11150502... | lld:pubmed |
| pubmed-article:11150502 | pubmed:meshHeading | pubmed-meshheading:11150502... | lld:pubmed |
| pubmed-article:11150502 | pubmed:meshHeading | pubmed-meshheading:11150502... | lld:pubmed |
| pubmed-article:11150502 | pubmed:year | 2000 | lld:pubmed |
| pubmed-article:11150502 | pubmed:articleTitle | Modulation of WHSC2 expression in human endothelial cells. | lld:pubmed |
| pubmed-article:11150502 | pubmed:affiliation | Department of Preclinical Sciences-LITA Vialba, University of Milano, Via G.B. Grassi, 74, 20157, Milan, Italy. | lld:pubmed |
| pubmed-article:11150502 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:11150502 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:7469 | entrezgene:pubmed | pubmed-article:11150502 | lld:entrezgene |
| entrez-gene:155871 | entrezgene:pubmed | pubmed-article:11150502 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:11150502 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:11150502 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11150502 | lld:pubmed |
