| pubmed-article:11125144 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:11125144 | lifeskim:mentions | umls-concept:C0002395 | lld:lifeskim |
| pubmed-article:11125144 | lifeskim:mentions | umls-concept:C0012655 | lld:lifeskim |
| pubmed-article:11125144 | lifeskim:mentions | umls-concept:C0008652 | lld:lifeskim |
| pubmed-article:11125144 | lifeskim:mentions | umls-concept:C1708726 | lld:lifeskim |
| pubmed-article:11125144 | pubmed:issue | 5500 | lld:pubmed |
| pubmed-article:11125144 | pubmed:dateCreated | 2000-12-28 | lld:pubmed |
| pubmed-article:11125144 | pubmed:abstractText | The apolipoprotein E (APOE) gene is the only genetic risk factor that has so far been linked to risk for late-onset Alzheimer's disease (LOAD). However, 50 percent of Alzheimer's disease cases do not carry an APOE4 allele, suggesting that other risk factors must exist. We performed a two-stage genome-wide screen in sibling pairs with LOAD to detect other susceptibility loci. Here we report evidence for an Alzheimer's disease locus on chromosome 10. Our stage one multipoint lod score (logarithm of the odds ratio for linkage/no linkage) of 2.48 (266 sibling pairs) increased to 3.83 in stage 2 (429 sibling pairs) close to D10S1225 (79 centimorgans). This locus modifies risk for Alzheimer's disease independent of APOE genotype. | lld:pubmed |
| pubmed-article:11125144 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11125144 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11125144 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11125144 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11125144 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:11125144 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11125144 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11125144 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11125144 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11125144 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:11125144 | pubmed:issn | 0036-8075 | lld:pubmed |
| pubmed-article:11125144 | pubmed:author | pubmed-author:NIWACC | lld:pubmed |
| pubmed-article:11125144 | pubmed:author | pubmed-author:WilliamsJJ | lld:pubmed |
| pubmed-article:11125144 | pubmed:author | pubmed-author:AbrahamRR | lld:pubmed |
| pubmed-article:11125144 | pubmed:author | pubmed-author:HardyJJ | lld:pubmed |
| pubmed-article:11125144 | pubmed:author | pubmed-author:MeyerDD | lld:pubmed |
| pubmed-article:11125144 | pubmed:author | pubmed-author:MyersAA | lld:pubmed |
| pubmed-article:11125144 | pubmed:author | pubmed-author:CrookRR | lld:pubmed |
| pubmed-article:11125144 | pubmed:author | pubmed-author:JonesLL | lld:pubmed |
| pubmed-article:11125144 | pubmed:author | pubmed-author:KwohDD | lld:pubmed |
| pubmed-article:11125144 | pubmed:author | pubmed-author:KehoePP | lld:pubmed |
| pubmed-article:11125144 | pubmed:author | pubmed-author:BoothJJ | lld:pubmed |
| pubmed-article:11125144 | pubmed:author | pubmed-author:SheardBB | lld:pubmed |
| pubmed-article:11125144 | pubmed:author | pubmed-author:RichCC | lld:pubmed |
| pubmed-article:11125144 | pubmed:author | pubmed-author:MarshallHH | lld:pubmed |
| pubmed-article:11125144 | pubmed:author | pubmed-author:GreenY NYN | lld:pubmed |
| pubmed-article:11125144 | pubmed:author | pubmed-author:LovestoneSS | lld:pubmed |
| pubmed-article:11125144 | pubmed:author | pubmed-author:HamshereMM | lld:pubmed |
| pubmed-article:11125144 | pubmed:author | pubmed-author:HolmansPP | lld:pubmed |
| pubmed-article:11125144 | pubmed:author | pubmed-author:RamiaJJ | lld:pubmed |
| pubmed-article:11125144 | pubmed:author | pubmed-author:CartySS | lld:pubmed |
| pubmed-article:11125144 | pubmed:author | pubmed-author:Perez-TurJJ | lld:pubmed |
| pubmed-article:11125144 | pubmed:author | pubmed-author:TunstallNN | lld:pubmed |
| pubmed-article:11125144 | pubmed:author | pubmed-author:DeVriezeF WFW | lld:pubmed |
| pubmed-article:11125144 | pubmed:author | pubmed-author:RudrasinghamV... | lld:pubmed |
| pubmed-article:11125144 | pubmed:author | pubmed-author:LillystoneSS | lld:pubmed |
| pubmed-article:11125144 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11125144 | pubmed:day | 22 | lld:pubmed |
| pubmed-article:11125144 | pubmed:volume | 290 | lld:pubmed |
| pubmed-article:11125144 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11125144 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11125144 | pubmed:pagination | 2304-5 | lld:pubmed |
| pubmed-article:11125144 | pubmed:dateRevised | 2010-11-18 | lld:pubmed |
| pubmed-article:11125144 | pubmed:meshHeading | pubmed-meshheading:11125144... | lld:pubmed |
| pubmed-article:11125144 | pubmed:meshHeading | pubmed-meshheading:11125144... | lld:pubmed |
| pubmed-article:11125144 | pubmed:meshHeading | pubmed-meshheading:11125144... | lld:pubmed |
| pubmed-article:11125144 | pubmed:meshHeading | pubmed-meshheading:11125144... | lld:pubmed |
| pubmed-article:11125144 | pubmed:meshHeading | pubmed-meshheading:11125144... | lld:pubmed |
| pubmed-article:11125144 | pubmed:meshHeading | pubmed-meshheading:11125144... | lld:pubmed |
| pubmed-article:11125144 | pubmed:meshHeading | pubmed-meshheading:11125144... | lld:pubmed |
| pubmed-article:11125144 | pubmed:meshHeading | pubmed-meshheading:11125144... | lld:pubmed |
| pubmed-article:11125144 | pubmed:meshHeading | pubmed-meshheading:11125144... | lld:pubmed |
| pubmed-article:11125144 | pubmed:meshHeading | pubmed-meshheading:11125144... | lld:pubmed |
| pubmed-article:11125144 | pubmed:meshHeading | pubmed-meshheading:11125144... | lld:pubmed |
| pubmed-article:11125144 | pubmed:meshHeading | pubmed-meshheading:11125144... | lld:pubmed |
| pubmed-article:11125144 | pubmed:meshHeading | pubmed-meshheading:11125144... | lld:pubmed |
| pubmed-article:11125144 | pubmed:meshHeading | pubmed-meshheading:11125144... | lld:pubmed |
| pubmed-article:11125144 | pubmed:meshHeading | pubmed-meshheading:11125144... | lld:pubmed |
| pubmed-article:11125144 | pubmed:year | 2000 | lld:pubmed |
| pubmed-article:11125144 | pubmed:articleTitle | Susceptibility locus for Alzheimer's disease on chromosome 10. | lld:pubmed |
| pubmed-article:11125144 | pubmed:affiliation | Department of Psychiatry, Washington University School of Medicine, 660 S. Euclid, St. Louis, MO 63110, USA. | lld:pubmed |
| pubmed-article:11125144 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:11125144 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:11125144 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:64851 | entrezgene:pubmed | pubmed-article:11125144 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11125144 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11125144 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11125144 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11125144 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11125144 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11125144 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11125144 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11125144 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11125144 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11125144 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11125144 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11125144 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11125144 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11125144 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11125144 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11125144 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11125144 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11125144 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11125144 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11125144 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11125144 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11125144 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11125144 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11125144 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11125144 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11125144 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11125144 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11125144 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11125144 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11125144 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11125144 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11125144 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11125144 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11125144 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11125144 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11125144 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11125144 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11125144 | lld:pubmed |
