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pubmed-article:1111432pubmed:abstractTextSeveral types of otoconia are present in the macular regions of young rats. These include multifaceted, transitional and rounded body forms, some variant otoconia and a few rhombohedrons. The adult form has typically rounded by nonsmooth body surfaces and pointed ends with three planar faces. The multifaceted and transitional otoconia fracture and etch more readily than do the adult type. The differences in properties of the otoconia are considered in the light of known facts concerning inorganic crystal nucleating and growth. This integrated approach indicates that many otoconia originate by seeding of multiple subunits on an organic substrate and develop by the mechanism of parallel growth. The basic structural unit is the rhombohedron. By analogy to inorganic crystals of calcite, it would seem that the typical otoconium grows on the end faces but growth on the side faces is suppressed by some unknown chemical factor. Some otoconia are exceptions, evidently seeding and growing in the pure rhombohedral form. Decalcification of cleaved otoconia shows that organic material is incorporated during growth. The observations are interpreted to indicate that organic substance influences growth and achievement of the adult otoconial form.lld:pubmed
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pubmed-article:1111432pubmed:authorpubmed-author:RossM DMDlld:pubmed
pubmed-article:1111432pubmed:authorpubmed-author:PeacorD RDRlld:pubmed
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pubmed-article:1111432pubmed:volume84lld:pubmed
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pubmed-article:1111432pubmed:pagination22-36lld:pubmed
pubmed-article:1111432pubmed:dateRevised2008-11-21lld:pubmed
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pubmed-article:1111432pubmed:articleTitleThe nature and crystal growth of otoconia in the rat.lld:pubmed
pubmed-article:1111432pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:1111432pubmed:publicationTypeResearch Support, U.S. Gov't, Non-P.H.S.lld:pubmed
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