To elucidate the function of human CASK/LIN-2, a novel member of membrane-associated guanylate kinase homologs family (MAGUK), by using the yeast two-hybrid system(LexA) to screen the protein interacting with the guanylate kinase-like domain(GK) of hCASK and identify possible protein that might involve downstream signal transduction of hCASK.
The United Laboratory of Signal Transductions, Burn Research Institute, Southwestern Hospital, the Third Military Medical University, Chongqing, 400038 P.R.China.
