| pubmed-article:11107692 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:11107692 | lifeskim:mentions | umls-concept:C0019348 | lld:lifeskim |
| pubmed-article:11107692 | lifeskim:mentions | umls-concept:C0927232 | lld:lifeskim |
| pubmed-article:11107692 | lifeskim:mentions | umls-concept:C1517499 | lld:lifeskim |
| pubmed-article:11107692 | lifeskim:mentions | umls-concept:C0442335 | lld:lifeskim |
| pubmed-article:11107692 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:11107692 | pubmed:dateCreated | 2001-1-5 | lld:pubmed |
| pubmed-article:11107692 | pubmed:abstractText | Manipulation of gene expression in developing or in mature central nervous systems (CNS) holds a promise for the resolution of many compelling neurobiological questions, including the feasibility of gene therapy to treat diseases of the brain. In this context, a number of viral vectors have been used in recent years to introduce and express genes into the CNS. This article discusses a gene transfer system based on the Herpes Simplex Virus-1 (HSV-1). We describe here the use of non-replicating, non-toxic HSV-1 vector, 8117/43, in a series of studies carried in our joint program. This vector proves further the utility of HSV-1 as a delivery vehicle to a number of distinct sites within the CNS. | lld:pubmed |
| pubmed-article:11107692 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11107692 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11107692 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11107692 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11107692 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11107692 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:11107692 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11107692 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11107692 | pubmed:issn | 0015-5659 | lld:pubmed |
| pubmed-article:11107692 | pubmed:author | pubmed-author:HorowitzJ MJM | lld:pubmed |
| pubmed-article:11107692 | pubmed:author | pubmed-author:TorresGG | lld:pubmed |
| pubmed-article:11107692 | pubmed:author | pubmed-author:LiaSS | lld:pubmed |
| pubmed-article:11107692 | pubmed:author | pubmed-author:StachowskiBB | lld:pubmed |
| pubmed-article:11107692 | pubmed:author | pubmed-author:StachowiakM... | lld:pubmed |
| pubmed-article:11107692 | pubmed:author | pubmed-author:BloomD CDC | lld:pubmed |
| pubmed-article:11107692 | pubmed:author | pubmed-author:StachowiakE... | lld:pubmed |
| pubmed-article:11107692 | pubmed:author | pubmed-author:GajdosíkováZZ | lld:pubmed |
| pubmed-article:11107692 | pubmed:author | pubmed-author:TranR KRK | lld:pubmed |
| pubmed-article:11107692 | pubmed:author | pubmed-author:GoulahCC | lld:pubmed |
| pubmed-article:11107692 | pubmed:author | pubmed-author:KorodyRR | lld:pubmed |
| pubmed-article:11107692 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11107692 | pubmed:volume | 59 | lld:pubmed |
| pubmed-article:11107692 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11107692 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11107692 | pubmed:pagination | 221-32 | lld:pubmed |
| pubmed-article:11107692 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:11107692 | pubmed:meshHeading | pubmed-meshheading:11107692... | lld:pubmed |
| pubmed-article:11107692 | pubmed:meshHeading | pubmed-meshheading:11107692... | lld:pubmed |
| pubmed-article:11107692 | pubmed:meshHeading | pubmed-meshheading:11107692... | lld:pubmed |
| pubmed-article:11107692 | pubmed:meshHeading | pubmed-meshheading:11107692... | lld:pubmed |
| pubmed-article:11107692 | pubmed:meshHeading | pubmed-meshheading:11107692... | lld:pubmed |
| pubmed-article:11107692 | pubmed:meshHeading | pubmed-meshheading:11107692... | lld:pubmed |
| pubmed-article:11107692 | pubmed:meshHeading | pubmed-meshheading:11107692... | lld:pubmed |
| pubmed-article:11107692 | pubmed:meshHeading | pubmed-meshheading:11107692... | lld:pubmed |
| pubmed-article:11107692 | pubmed:meshHeading | pubmed-meshheading:11107692... | lld:pubmed |
| pubmed-article:11107692 | pubmed:meshHeading | pubmed-meshheading:11107692... | lld:pubmed |
| pubmed-article:11107692 | pubmed:meshHeading | pubmed-meshheading:11107692... | lld:pubmed |
| pubmed-article:11107692 | pubmed:year | 2000 | lld:pubmed |
| pubmed-article:11107692 | pubmed:articleTitle | Gene transfer into the central nervous system using herpes simplex virus-1 vectors. | lld:pubmed |
| pubmed-article:11107692 | pubmed:affiliation | Department of Anatomy and Cell Biology, State University of New York, Buffalo, USA. | lld:pubmed |
| pubmed-article:11107692 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:11107692 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:11107692 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| pubmed-article:11107692 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11107692 | lld:pubmed |
