| pubmed-article:1109390 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1109390 | lifeskim:mentions | umls-concept:C0021936 | lld:lifeskim |
| pubmed-article:1109390 | lifeskim:mentions | umls-concept:C0001811 | lld:lifeskim |
| pubmed-article:1109390 | lifeskim:mentions | umls-concept:C0025914 | lld:lifeskim |
| pubmed-article:1109390 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
| pubmed-article:1109390 | lifeskim:mentions | umls-concept:C0006104 | lld:lifeskim |
| pubmed-article:1109390 | lifeskim:mentions | umls-concept:C0041485 | lld:lifeskim |
| pubmed-article:1109390 | lifeskim:mentions | umls-concept:C1533691 | lld:lifeskim |
| pubmed-article:1109390 | lifeskim:mentions | umls-concept:C1709474 | lld:lifeskim |
| pubmed-article:1109390 | lifeskim:mentions | umls-concept:C0439799 | lld:lifeskim |
| pubmed-article:1109390 | lifeskim:mentions | umls-concept:C1519355 | lld:lifeskim |
| pubmed-article:1109390 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:1109390 | pubmed:dateCreated | 1975-3-14 | lld:pubmed |
| pubmed-article:1109390 | pubmed:abstractText | The effect of age on active transport of catecholamine precursors was studied in a healthy population of mature (12-mo.-old) and senescent (30-mo.-old) C57BL/6J male mice. No age differences were observed in uptake of L-(3H)-tyrosine IN VITRO by slices of hypothalamus, brain stem, and striatum at external concentrations equal to or greater than blood levels. However, age-related reductions were observed intermittently in the hypothalamus, brain stem, and striatum at very low concentrations of tyrosine (less than 10 pg/ml). No age differences were observed in incorporation of L-(3H)-tyrosine into hypothalamic proteins when corrected for intracellular uptake of L-(3H)-tyrosine. No age differences were observed in uptake of L-(3H)-DOPA. The possible contribution of age-related changes in extra-cellular space to decreased uptake was determined to be negligible by wash-out studies of tyrosine and by the uptake of inulin. A significant age-related increase of inulin uptake IN VITRO was observed under ionic conditions which minimize tissue swelling. | lld:pubmed |
| pubmed-article:1109390 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1109390 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1109390 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:1109390 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1109390 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1109390 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1109390 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1109390 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1109390 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:1109390 | pubmed:issn | 0022-1422 | lld:pubmed |
| pubmed-article:1109390 | pubmed:author | pubmed-author:JonesFF | lld:pubmed |
| pubmed-article:1109390 | pubmed:author | pubmed-author:FinchC ECE | lld:pubmed |
| pubmed-article:1109390 | pubmed:author | pubmed-author:WalkerJ PJP | lld:pubmed |
| pubmed-article:1109390 | pubmed:author | pubmed-author:HodyGG | lld:pubmed |
| pubmed-article:1109390 | pubmed:author | pubmed-author:Morton-SmithW... | lld:pubmed |
| pubmed-article:1109390 | pubmed:author | pubmed-author:AlperAA | lld:pubmed |
| pubmed-article:1109390 | pubmed:author | pubmed-author:DougherG... | lld:pubmed |
| pubmed-article:1109390 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1109390 | pubmed:volume | 30 | lld:pubmed |
| pubmed-article:1109390 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1109390 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1109390 | pubmed:pagination | 33-40 | lld:pubmed |
| pubmed-article:1109390 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:1109390 | pubmed:meshHeading | pubmed-meshheading:1109390-... | lld:pubmed |
| pubmed-article:1109390 | pubmed:meshHeading | pubmed-meshheading:1109390-... | lld:pubmed |
| pubmed-article:1109390 | pubmed:meshHeading | pubmed-meshheading:1109390-... | lld:pubmed |
| pubmed-article:1109390 | pubmed:meshHeading | pubmed-meshheading:1109390-... | lld:pubmed |
| pubmed-article:1109390 | pubmed:meshHeading | pubmed-meshheading:1109390-... | lld:pubmed |
| pubmed-article:1109390 | pubmed:meshHeading | pubmed-meshheading:1109390-... | lld:pubmed |
| pubmed-article:1109390 | pubmed:meshHeading | pubmed-meshheading:1109390-... | lld:pubmed |
| pubmed-article:1109390 | pubmed:meshHeading | pubmed-meshheading:1109390-... | lld:pubmed |
| pubmed-article:1109390 | pubmed:meshHeading | pubmed-meshheading:1109390-... | lld:pubmed |
| pubmed-article:1109390 | pubmed:meshHeading | pubmed-meshheading:1109390-... | lld:pubmed |
| pubmed-article:1109390 | pubmed:meshHeading | pubmed-meshheading:1109390-... | lld:pubmed |
| pubmed-article:1109390 | pubmed:meshHeading | pubmed-meshheading:1109390-... | lld:pubmed |
| pubmed-article:1109390 | pubmed:meshHeading | pubmed-meshheading:1109390-... | lld:pubmed |
| pubmed-article:1109390 | pubmed:meshHeading | pubmed-meshheading:1109390-... | lld:pubmed |
| pubmed-article:1109390 | pubmed:year | 1975 | lld:pubmed |
| pubmed-article:1109390 | pubmed:articleTitle | Aging and the passage of L-tyrosine, L-DOPA, and inulin into mouse brain slices in vitro. | lld:pubmed |
| pubmed-article:1109390 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1109390 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:1109390 | pubmed:publicationType | In Vitro | lld:pubmed |
| pubmed-article:1109390 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:1109390 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
