| pubmed-article:11073928 | rdf:type | pubmed:Citation | lld:pubmed |
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| pubmed-article:11073928 | lifeskim:mentions | umls-concept:C0178666 | lld:lifeskim |
| pubmed-article:11073928 | lifeskim:mentions | umls-concept:C0851285 | lld:lifeskim |
| pubmed-article:11073928 | lifeskim:mentions | umls-concept:C1547699 | lld:lifeskim |
| pubmed-article:11073928 | lifeskim:mentions | umls-concept:C2700640 | lld:lifeskim |
| pubmed-article:11073928 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:11073928 | lifeskim:mentions | umls-concept:C0019487 | lld:lifeskim |
| pubmed-article:11073928 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:11073928 | pubmed:issue | 23 | lld:pubmed |
| pubmed-article:11073928 | pubmed:dateCreated | 2000-11-27 | lld:pubmed |
| pubmed-article:11073928 | pubmed:abstractText | Glucose transport kinetics and mRNA levels of different glucose transporters were determined in Saccharomyces cerevisiae strains expressing different sugar kinases. During exponential growth on glucose, a hxk2 null strain exhibited high-affinity hexose transport associated with an elevated transcription of the genes HXT2 and HXT7, encoding high-affinity transporters, and a diminished expression of the HXT1 and HXT3 genes, encoding low-affinity transporters. Deletion of HXT7 revealed that the high-affinity component is mostly due to HXT7; however, a previously unidentified very-high-affinity component (K(m) = 0.19 mM) appeared to be due to other factors. Expression of genes encoding hexokinases from Schizosaccharomyces pombe or Yarrowia lipolytica in a hxk1 hxk2 glk1 strain prevented derepression of the high-affinity transport system at high concentrations of glucose. | lld:pubmed |
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| pubmed-article:11073928 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:11073928 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:11073928 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11073928 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:11073928 | pubmed:issn | 0021-9193 | lld:pubmed |
| pubmed-article:11073928 | pubmed:author | pubmed-author:Van DamKK | lld:pubmed |
| pubmed-article:11073928 | pubmed:author | pubmed-author:GancedoCC | lld:pubmed |
| pubmed-article:11073928 | pubmed:author | pubmed-author:KruckebergA... | lld:pubmed |
| pubmed-article:11073928 | pubmed:author | pubmed-author:PetitTT | lld:pubmed |
| pubmed-article:11073928 | pubmed:author | pubmed-author:DiderichJ AJA | lld:pubmed |
| pubmed-article:11073928 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11073928 | pubmed:volume | 182 | lld:pubmed |
| pubmed-article:11073928 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11073928 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11073928 | pubmed:pagination | 6815-8 | lld:pubmed |
| pubmed-article:11073928 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
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| pubmed-article:11073928 | pubmed:meshHeading | pubmed-meshheading:11073928... | lld:pubmed |
| pubmed-article:11073928 | pubmed:year | 2000 | lld:pubmed |
| pubmed-article:11073928 | pubmed:articleTitle | Hexokinase regulates kinetics of glucose transport and expression of genes encoding hexose transporters in Saccharomyces cerevisiae. | lld:pubmed |
| pubmed-article:11073928 | pubmed:affiliation | Instituto de Investigaciones Biomédicas Alberto Sols, 28029 Madrid, Spain. | lld:pubmed |
| pubmed-article:11073928 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:11073928 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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