| pubmed-article:11072139 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:11072139 | lifeskim:mentions | umls-concept:C0025914 | lld:lifeskim |
| pubmed-article:11072139 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
| pubmed-article:11072139 | lifeskim:mentions | umls-concept:C0006104 | lld:lifeskim |
| pubmed-article:11072139 | lifeskim:mentions | umls-concept:C0013794 | lld:lifeskim |
| pubmed-article:11072139 | lifeskim:mentions | umls-concept:C0002771 | lld:lifeskim |
| pubmed-article:11072139 | lifeskim:mentions | umls-concept:C0066908 | lld:lifeskim |
| pubmed-article:11072139 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:11072139 | lifeskim:mentions | umls-concept:C1948023 | lld:lifeskim |
| pubmed-article:11072139 | lifeskim:mentions | umls-concept:C0086597 | lld:lifeskim |
| pubmed-article:11072139 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
| pubmed-article:11072139 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:11072139 | pubmed:dateCreated | 2000-12-27 | lld:pubmed |
| pubmed-article:11072139 | pubmed:abstractText | This work was designed to examine whether brain endomorphins (EM1 and EM2), the endogenous mu-opioid ligands, are involved in electroacupuncture (EA)-induced analgesia in the mice. C57BL/6J mice were given EA for 30 min and the effect of EA-induced analgesia was assessed by radiant heat tail flick latency (TFL). Intracerebroventricular (i.c.v.) injection of mu-opioid receptor antagonist D-Phe-Cys-Tyr-D-Tyr-Orn-Thr-Pen-Thr-NH(2) (CTOP), or antiserum against EM1 or EM2 was performed to see whether EA analgesia could be blocked. The results showed that: (1) i.c.v. injection of CTOP at 25-100 ng dose-dependently antagonized the analgesia induced by EA of 2 Hz, but not 100 Hz. (2) Intracerebroventricular injection of EM1 antiserum (5 ml, 1:1 or 1:10 dilution) dose-dependently antagonized 2 Hz, but not 100 Hz EA analgesia. (3) EM2 antiserum showed similar effect at 1:1 dilution. The results are interpreted to mean that endogenously released EM1 and EM2 and the cerebral mu-receptors are involved in mediating 2 Hz but not 100 Hz EA analgesia in the mice. | lld:pubmed |
| pubmed-article:11072139 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11072139 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11072139 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11072139 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:11072139 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11072139 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11072139 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11072139 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11072139 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11072139 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11072139 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11072139 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11072139 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:11072139 | pubmed:issn | 0304-3940 | lld:pubmed |
| pubmed-article:11072139 | pubmed:author | pubmed-author:RAOT TTT | lld:pubmed |
| pubmed-article:11072139 | pubmed:author | pubmed-author:HuangCC | lld:pubmed |
| pubmed-article:11072139 | pubmed:author | pubmed-author:WangYY | lld:pubmed |
| pubmed-article:11072139 | pubmed:author | pubmed-author:ChangJ KJK | lld:pubmed |
| pubmed-article:11072139 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11072139 | pubmed:day | 24 | lld:pubmed |
| pubmed-article:11072139 | pubmed:volume | 294 | lld:pubmed |
| pubmed-article:11072139 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11072139 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11072139 | pubmed:pagination | 159-62 | lld:pubmed |
| pubmed-article:11072139 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:11072139 | pubmed:meshHeading | pubmed-meshheading:11072139... | lld:pubmed |
| pubmed-article:11072139 | pubmed:meshHeading | pubmed-meshheading:11072139... | lld:pubmed |
| pubmed-article:11072139 | pubmed:meshHeading | pubmed-meshheading:11072139... | lld:pubmed |
| pubmed-article:11072139 | pubmed:meshHeading | pubmed-meshheading:11072139... | lld:pubmed |
| pubmed-article:11072139 | pubmed:meshHeading | pubmed-meshheading:11072139... | lld:pubmed |
| pubmed-article:11072139 | pubmed:meshHeading | pubmed-meshheading:11072139... | lld:pubmed |
| pubmed-article:11072139 | pubmed:meshHeading | pubmed-meshheading:11072139... | lld:pubmed |
| pubmed-article:11072139 | pubmed:meshHeading | pubmed-meshheading:11072139... | lld:pubmed |
| pubmed-article:11072139 | pubmed:meshHeading | pubmed-meshheading:11072139... | lld:pubmed |
| pubmed-article:11072139 | pubmed:meshHeading | pubmed-meshheading:11072139... | lld:pubmed |
| pubmed-article:11072139 | pubmed:meshHeading | pubmed-meshheading:11072139... | lld:pubmed |
| pubmed-article:11072139 | pubmed:year | 2000 | lld:pubmed |
| pubmed-article:11072139 | pubmed:articleTitle | Endomorphin and mu-opioid receptors in mouse brain mediate the analgesic effect induced by 2 Hz but not 100 Hz electroacupuncture stimulation. | lld:pubmed |
| pubmed-article:11072139 | pubmed:affiliation | Neuroscience Research Institute, Peking University, 38 Xue Yuan Road, 100083, PR, Beijing, China. | lld:pubmed |
| pubmed-article:11072139 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:11072139 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:11072139 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11072139 | lld:pubmed |
