| pubmed-article:11055333 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:11055333 | lifeskim:mentions | umls-concept:C0439849 | lld:lifeskim |
| pubmed-article:11055333 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:11055333 | lifeskim:mentions | umls-concept:C0243076 | lld:lifeskim |
| pubmed-article:11055333 | lifeskim:mentions | umls-concept:C0445223 | lld:lifeskim |
| pubmed-article:11055333 | lifeskim:mentions | umls-concept:C0991876 | lld:lifeskim |
| pubmed-article:11055333 | lifeskim:mentions | umls-concept:C1704737 | lld:lifeskim |
| pubmed-article:11055333 | lifeskim:mentions | umls-concept:C0221874 | lld:lifeskim |
| pubmed-article:11055333 | lifeskim:mentions | umls-concept:C1552599 | lld:lifeskim |
| pubmed-article:11055333 | lifeskim:mentions | umls-concept:C0205549 | lld:lifeskim |
| pubmed-article:11055333 | lifeskim:mentions | umls-concept:C1704787 | lld:lifeskim |
| pubmed-article:11055333 | lifeskim:mentions | umls-concept:C0068389 | lld:lifeskim |
| pubmed-article:11055333 | pubmed:issue | 20 | lld:pubmed |
| pubmed-article:11055333 | pubmed:dateCreated | 2001-2-20 | lld:pubmed |
| pubmed-article:11055333 | pubmed:abstractText | The study of kappa-opioid receptor function in vivo has been hampered by the limited choice of selective kappa-antagonists. Recently discovered kappa-antagonists have not yet been utilised in vivo. We here report the synthesis and in vitro evaluation of a new amidine derivative of naltrindole. It showed substantially greater kappa-selectivity in binding assays than known analogues with shorter spacer in the amidine side chain. This indicates that in nor-BNI and related selective kappa-antagonists, the second basic centre may not be ideally located. | lld:pubmed |
| pubmed-article:11055333 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11055333 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11055333 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11055333 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11055333 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:11055333 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11055333 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11055333 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11055333 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11055333 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11055333 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11055333 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11055333 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11055333 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11055333 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11055333 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11055333 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11055333 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:11055333 | pubmed:issn | 0960-894X | lld:pubmed |
| pubmed-article:11055333 | pubmed:author | pubmed-author:LewisJ WJW | lld:pubmed |
| pubmed-article:11055333 | pubmed:author | pubmed-author:HusbandsS MSM | lld:pubmed |
| pubmed-article:11055333 | pubmed:author | pubmed-author:JalesA RAR | lld:pubmed |
| pubmed-article:11055333 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11055333 | pubmed:day | 16 | lld:pubmed |
| pubmed-article:11055333 | pubmed:volume | 10 | lld:pubmed |
| pubmed-article:11055333 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11055333 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11055333 | pubmed:pagination | 2259-61 | lld:pubmed |
| pubmed-article:11055333 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:11055333 | pubmed:meshHeading | pubmed-meshheading:11055333... | lld:pubmed |
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| pubmed-article:11055333 | pubmed:meshHeading | pubmed-meshheading:11055333... | lld:pubmed |
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| pubmed-article:11055333 | pubmed:meshHeading | pubmed-meshheading:11055333... | lld:pubmed |
| pubmed-article:11055333 | pubmed:meshHeading | pubmed-meshheading:11055333... | lld:pubmed |
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| pubmed-article:11055333 | pubmed:meshHeading | pubmed-meshheading:11055333... | lld:pubmed |
| pubmed-article:11055333 | pubmed:meshHeading | pubmed-meshheading:11055333... | lld:pubmed |
| pubmed-article:11055333 | pubmed:meshHeading | pubmed-meshheading:11055333... | lld:pubmed |
| pubmed-article:11055333 | pubmed:meshHeading | pubmed-meshheading:11055333... | lld:pubmed |
| pubmed-article:11055333 | pubmed:meshHeading | pubmed-meshheading:11055333... | lld:pubmed |
| pubmed-article:11055333 | pubmed:meshHeading | pubmed-meshheading:11055333... | lld:pubmed |
| pubmed-article:11055333 | pubmed:meshHeading | pubmed-meshheading:11055333... | lld:pubmed |
| pubmed-article:11055333 | pubmed:year | 2000 | lld:pubmed |
| pubmed-article:11055333 | pubmed:articleTitle | Selective kappa-opioid antagonists related to naltrindole. Effect of side-chain spacer in the 5'-amidinoalkyl series. | lld:pubmed |
| pubmed-article:11055333 | pubmed:affiliation | School of Chemistry, University of Bristol, UK. | lld:pubmed |
| pubmed-article:11055333 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:11055333 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:11055333 | lld:chembl |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11055333 | lld:pubmed |
