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pubmed-article:11029781rdf:typepubmed:Citationlld:pubmed
pubmed-article:11029781lifeskim:mentionsumls-concept:C0006142lld:lifeskim
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pubmed-article:11029781pubmed:issue2lld:pubmed
pubmed-article:11029781pubmed:dateCreated2001-1-26lld:pubmed
pubmed-article:11029781pubmed:abstractTextAlthough the role of axillary lymph node dissection is controversial with respect to survival benefits, its role as a staging procedure has been well established since nodal involvement is the most reliable prognostic indicator for patients with breast cancer. Selective sentinel lymph node (SLN) dissection is gaining acceptance as a useful staging procedure because it is minimally invasive and spares approximately 70-80% of the patients a more extensive axillary lymph node dissection. The evolving techniques for selective SLN dissection using blue dye and radiotracer methods are reviewed in this article. Based on the classic definition of the breast lymphatic drainage and recently published articles addressing the issue of peritumoral and intradermal injections, a possible new and simplified approach using intradermal injection may identify the axillary SLN more quickly and reliably. This article emphasizes the importance of a multidisciplinary approach in the identification of SLNs by preoperative lymphoscintigraphy performed by expert nuclear medicine physicians, the intraoperative mapping and harvesting of SLNs by well trained surgeons and the meticulous examination of SLNs by experienced pathologists. Therefore, to achieve the highest rate of accuracy regarding SLN status, it is imperative that a multidisciplinary team with close communication and cooperation be formed. The clinical significance of SLNs will be determined by results from follow-up and clinical trials.lld:pubmed
pubmed-article:11029781pubmed:languageenglld:pubmed
pubmed-article:11029781pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
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pubmed-article:11029781pubmed:statusMEDLINElld:pubmed
pubmed-article:11029781pubmed:issn1340-6868lld:pubmed
pubmed-article:11029781pubmed:authorpubmed-author:LeongS PSPlld:pubmed
pubmed-article:11029781pubmed:authorpubmed-author:WongJ HJHlld:pubmed
pubmed-article:11029781pubmed:authorpubmed-author:TreselerP APAlld:pubmed
pubmed-article:11029781pubmed:authorpubmed-author:MoritaE TETlld:pubmed
pubmed-article:11029781pubmed:issnTypePrintlld:pubmed
pubmed-article:11029781pubmed:volume7lld:pubmed
pubmed-article:11029781pubmed:ownerNLMlld:pubmed
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pubmed-article:11029781pubmed:pagination105-13lld:pubmed
pubmed-article:11029781pubmed:dateRevised2004-11-17lld:pubmed
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pubmed-article:11029781pubmed:year2000lld:pubmed
pubmed-article:11029781pubmed:articleTitleMultidisciplinary approach to selective sentinel lymph node mapping in breast cancer.lld:pubmed
pubmed-article:11029781pubmed:affiliationDepartment of Surgery, University of California at San Francisco, School of Medicine, UCSF Comprehensive Cancer Center and Mount Zion Medical Center, 1600 Divisadero Street, Box 1674, San Francisco, CA 94115, USA.lld:pubmed
pubmed-article:11029781pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:11029781pubmed:publicationTypeReviewlld:pubmed