| pubmed-article:10957727 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10957727 | lifeskim:mentions | umls-concept:C0019707 | lld:lifeskim |
| pubmed-article:10957727 | lifeskim:mentions | umls-concept:C0237401 | lld:lifeskim |
| pubmed-article:10957727 | lifeskim:mentions | umls-concept:C0001737 | lld:lifeskim |
| pubmed-article:10957727 | lifeskim:mentions | umls-concept:C0205147 | lld:lifeskim |
| pubmed-article:10957727 | lifeskim:mentions | umls-concept:C0314603 | lld:lifeskim |
| pubmed-article:10957727 | lifeskim:mentions | umls-concept:C1705493 | lld:lifeskim |
| pubmed-article:10957727 | lifeskim:mentions | umls-concept:C0018387 | lld:lifeskim |
| pubmed-article:10957727 | lifeskim:mentions | umls-concept:C2827666 | lld:lifeskim |
| pubmed-article:10957727 | pubmed:issue | 13 | lld:pubmed |
| pubmed-article:10957727 | pubmed:dateCreated | 2000-9-27 | lld:pubmed |
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| pubmed-article:10957727 | pubmed:abstractText | The V3 loop of both HIV-1 and HIV-2 is characterized by a high degree of genetic variation. To investigate the spectrum of HIV-2 variability in nature we have focused on the C2V3 region of Env and analyzed 108 viral sequences obtained from uncultured peripheral blood mononuclear cells obtained from 16 HIV-2-seropositive individuals from Bissau (Guinea-Bissau). The estimated values of genetic divergence between individuals were higher than those calculated from sequence information collected in a single individual. We have also found that the sequences surrounding the V3 loop contribute significantly to the overall genetic diversity of the C2V3 region of HIV-2 gp105, while the V3 loop itself seems to be rather conserved. Phylogenetic analysis demonstrated that all the individuals enrolled in this study were infected with HIV-2 subtype A viruses. | lld:pubmed |
| pubmed-article:10957727 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10957727 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
