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pubmed-article:10952242pubmed:abstractTextGlutamine synthetase (GS) catalyzes the synthesis of glutamine, a major energy source of cells, and is upregulated in a subset of human hepatocellular carcinomas (HCCs). GS expression may be related to tumor recurrence, since GS-expressing tumors have a growth advantage in that they are independent of the extracellular glutamine supply. However, there are no studies concerning the prognostic value of GS expression in patients with HCC.lld:pubmed
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pubmed-article:10952242pubmed:articleTitlePrognostic significance of glutamine synthetase expression in unifocal advanced hepatocellular carcinoma.lld:pubmed
pubmed-article:10952242pubmed:affiliationDepartment of Surgical Oncology, Graduate School of Medicine, University of Tokyo, Japan. OSADA-1SU@h.u-tokyo.ac.jplld:pubmed
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