There have been relatively few quantitative MRI studies of temporal lobe structures and the lateral ventricles in bipolar patients and a lack of agreement across studies as to whether these structures differ significantly in size from control subjects. Also there have been no quantitative MRI studies of bipolar II patients. The present study measured temporal lobe and ventricular structures in both bipolar I and bipolar II patients, as well as control subjects.
Department of Psychiatry, University of Maryland Medical Center and Psychiatry Service, Baltimore VA Medical Center, 10 North Greene Street, Baltimore, MD 21201, USA. peter.hauser@med.va.gov