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pubmed-article:10936822pubmed:abstractTextAlthough left ventricular (LV) dysfunction has been described after subarachnoid hemorrhage (SAH), its pathophysiology, regional distribution, and reversibility remain uncertain. To test the hypothesis that regional wall motion patterns in SAH patients do not match the typical patterns observed in coronary artery disease, a segmental wall motion analysis was performed in 30 SAH patients with LV dysfunction. Both regional (n = 21) and global (n = 9) wall motion patterns were observed. Preservation of apical function relative to the base was observed in 17 (57%) of the 30 patients. Many of the wall motion patterns were atypical of coronary artery disease but correlated with the distribution of the myocardial sympathetic nerve terminals. Five subjects had follow-up echocardiograms with resolution of LV dysfunction in all cases. In conclusion, a previously unreported, apex-sparing pattern of LV dysfunction is described, providing indirect evidence for a neurally mediated mechanism of cardiac injury. Limited data indicate that LV dysfunction in SAH patients is potentially reversible.lld:pubmed
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pubmed-article:10936822pubmed:authorpubmed-author:PicardM HMHlld:pubmed
pubmed-article:10936822pubmed:authorpubmed-author:ZaroffJ GJGlld:pubmed
pubmed-article:10936822pubmed:authorpubmed-author:RordorfG AGAlld:pubmed
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pubmed-article:10936822pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:10936822pubmed:year2000lld:pubmed
pubmed-article:10936822pubmed:articleTitleRegional patterns of left ventricular systolic dysfunction after subarachnoid hemorrhage: evidence for neurally mediated cardiac injury.lld:pubmed
pubmed-article:10936822pubmed:affiliationMassachusetts General Hospital, Boston 02114, USA.lld:pubmed
pubmed-article:10936822pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:10936822pubmed:publicationTypeComparative Studylld:pubmed
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