Identification of a novel inhibitor specific to the fungal chitin synthase. Inhibition of chitin synthase 1 arrests the cell growth, but inhibition of chitin synthase 1 and 2 is lethal in the pathogenic fungus Candida albicans.

Source:http://linkedlifedata.com/resource/pubmed/id/10930406

J. Biol. Chem. 2000 Oct 20 275 42 32901-5

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PMID
10930406