| pubmed-article:10926322 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10926322 | lifeskim:mentions | umls-concept:C0011860 | lld:lifeskim |
| pubmed-article:10926322 | lifeskim:mentions | umls-concept:C0035309 | lld:lifeskim |
| pubmed-article:10926322 | lifeskim:mentions | umls-concept:C0023401 | lld:lifeskim |
| pubmed-article:10926322 | lifeskim:mentions | umls-concept:C0033382 | lld:lifeskim |
| pubmed-article:10926322 | lifeskim:mentions | umls-concept:C0332281 | lld:lifeskim |
| pubmed-article:10926322 | lifeskim:mentions | umls-concept:C1417815 | lld:lifeskim |
| pubmed-article:10926322 | lifeskim:mentions | umls-concept:C1882417 | lld:lifeskim |
| pubmed-article:10926322 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:10926322 | pubmed:dateCreated | 2000-11-13 | lld:pubmed |
| pubmed-article:10926322 | pubmed:abstractText | In this study we tested the hypothesis that the Leu7Pro7 polymorphism in prepro neuropeptide Y (NPY) gene could be a risk marker for the development of diabetic retinopathy and analyzed a well characterized cohort of patients with Type 2 diabetes followed-up for 10 years from the time of diagnosis. The frequency of Leu7/Pro7-polymorphism was 9.3% (8 out of 86). At baseline, the frequency of retinopathy in patients with the Leu7/Pro7-polymorphism was 25% (2 out of 8) and in those without it 6.4% (5 out of 78) (p=0.126). At 10-year the respective figures were 88% and 50% (p=-0.040). The odds ratio for Leu7/Pro7-polymorphism in logistic regression analysis adjusted for age, gender and HbA1c was 8.97 (95% confidence intervals 1.09-98.0; p=0.049). Our finding based on elderly Finnish Type 2 diabetic subjects suggests that the Leu7Pro7-genotype in preproNPY gene is associated with the development of diabetic retinopathy. | lld:pubmed |
| pubmed-article:10926322 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10926322 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10926322 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10926322 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10926322 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10926322 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10926322 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10926322 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10926322 | pubmed:issn | 0947-7349 | lld:pubmed |
| pubmed-article:10926322 | pubmed:author | pubmed-author:KouluMM | lld:pubmed |
| pubmed-article:10926322 | pubmed:author | pubmed-author:LaaksoMM | lld:pubmed |
| pubmed-article:10926322 | pubmed:author | pubmed-author:NiskanenLL | lld:pubmed |
| pubmed-article:10926322 | pubmed:author | pubmed-author:UusitupaM IMI | lld:pubmed |
| pubmed-article:10926322 | pubmed:author | pubmed-author:PesonenUU | lld:pubmed |
| pubmed-article:10926322 | pubmed:author | pubmed-author:TeräsvirtaMM | lld:pubmed |
| pubmed-article:10926322 | pubmed:author | pubmed-author:ValveRR | lld:pubmed |
| pubmed-article:10926322 | pubmed:author | pubmed-author:KarvonenM KMK | lld:pubmed |
| pubmed-article:10926322 | pubmed:author | pubmed-author:Voutilainen-K... | lld:pubmed |
| pubmed-article:10926322 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10926322 | pubmed:volume | 108 | lld:pubmed |
| pubmed-article:10926322 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10926322 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10926322 | pubmed:pagination | 235-6 | lld:pubmed |
| pubmed-article:10926322 | pubmed:dateRevised | 2004-11-17 | lld:pubmed |
| pubmed-article:10926322 | pubmed:meshHeading | pubmed-meshheading:10926322... | lld:pubmed |
| pubmed-article:10926322 | pubmed:meshHeading | pubmed-meshheading:10926322... | lld:pubmed |
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| pubmed-article:10926322 | pubmed:meshHeading | pubmed-meshheading:10926322... | lld:pubmed |
| pubmed-article:10926322 | pubmed:meshHeading | pubmed-meshheading:10926322... | lld:pubmed |
| pubmed-article:10926322 | pubmed:meshHeading | pubmed-meshheading:10926322... | lld:pubmed |
| pubmed-article:10926322 | pubmed:meshHeading | pubmed-meshheading:10926322... | lld:pubmed |
| pubmed-article:10926322 | pubmed:meshHeading | pubmed-meshheading:10926322... | lld:pubmed |
| pubmed-article:10926322 | pubmed:meshHeading | pubmed-meshheading:10926322... | lld:pubmed |
| pubmed-article:10926322 | pubmed:meshHeading | pubmed-meshheading:10926322... | lld:pubmed |
| pubmed-article:10926322 | pubmed:year | 2000 | lld:pubmed |
| pubmed-article:10926322 | pubmed:articleTitle | Leucine 7 to proline 7 polymorphism in the neuropeptide y gene is associated with retinopathy in type 2 diabetes. | lld:pubmed |
| pubmed-article:10926322 | pubmed:affiliation | Department of Clinical Nutrition, University of Kuopio, Finland. leo.niskanen@kuh.fi | lld:pubmed |
| pubmed-article:10926322 | pubmed:publicationType | Journal Article | lld:pubmed |
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| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10926322 | lld:pubmed |
