| pubmed-article:10921905 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10921905 | lifeskim:mentions | umls-concept:C1333887 | lld:lifeskim |
| pubmed-article:10921905 | lifeskim:mentions | umls-concept:C1334091 | lld:lifeskim |
| pubmed-article:10921905 | lifeskim:mentions | umls-concept:C1708726 | lld:lifeskim |
| pubmed-article:10921905 | lifeskim:mentions | umls-concept:C0040649 | lld:lifeskim |
| pubmed-article:10921905 | lifeskim:mentions | umls-concept:C0221463 | lld:lifeskim |
| pubmed-article:10921905 | pubmed:issue | 15 | lld:pubmed |
| pubmed-article:10921905 | pubmed:dateCreated | 2000-9-8 | lld:pubmed |
| pubmed-article:10921905 | pubmed:abstractText | Igf2 and H19 exhibit parent-of-origin-specific monoallelic expression. H19 is expressed from the maternal chromosome and Igf2 from the paternal. The two genes share enhancer elements and monoallelic expression of both genes is dependent on cis-acting sequences upstream of the H19 promoter. In this work we examine the mechanisms by which this region silences the maternal Igf2 allele and we demonstrate that deletion of this region can result in high levels of activation of both H19 and Igf2 from a single chromosome. Moreover, by inserting this cis element between a promoter and its enhancer at a heterologous position, we demonstrate that the sequences carry both insulator activity and the ability to be stably imprinted. We also characterize the insulator in vitro and show that it is neither enhancer nor promoter specific. | lld:pubmed |
| pubmed-article:10921905 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10921905 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10921905 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10921905 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10921905 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:10921905 | pubmed:issn | 0890-9369 | lld:pubmed |
| pubmed-article:10921905 | pubmed:author | pubmed-author:SrivastavaMM | lld:pubmed |
| pubmed-article:10921905 | pubmed:author | pubmed-author:IvenHH | lld:pubmed |
| pubmed-article:10921905 | pubmed:author | pubmed-author:MunkKK | lld:pubmed |
| pubmed-article:10921905 | pubmed:author | pubmed-author:HuangS PSP | lld:pubmed |
| pubmed-article:10921905 | pubmed:author | pubmed-author:GrinbergAA | lld:pubmed |
| pubmed-article:10921905 | pubmed:author | pubmed-author:HsiehSS | lld:pubmed |
| pubmed-article:10921905 | pubmed:author | pubmed-author:BatlleJJ | lld:pubmed |
| pubmed-article:10921905 | pubmed:author | pubmed-author:PfeiferKK | lld:pubmed |
| pubmed-article:10921905 | pubmed:author | pubmed-author:KafferC RCR | lld:pubmed |
| pubmed-article:10921905 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10921905 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:10921905 | pubmed:volume | 14 | lld:pubmed |
| pubmed-article:10921905 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10921905 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10921905 | pubmed:pagination | 1908-19 | lld:pubmed |
| pubmed-article:10921905 | pubmed:dateRevised | 2011-10-7 | lld:pubmed |
| pubmed-article:10921905 | pubmed:meshHeading | pubmed-meshheading:10921905... | lld:pubmed |
| pubmed-article:10921905 | pubmed:meshHeading | pubmed-meshheading:10921905... | lld:pubmed |
| pubmed-article:10921905 | pubmed:meshHeading | pubmed-meshheading:10921905... | lld:pubmed |
| pubmed-article:10921905 | pubmed:meshHeading | pubmed-meshheading:10921905... | lld:pubmed |
| pubmed-article:10921905 | pubmed:meshHeading | pubmed-meshheading:10921905... | lld:pubmed |
| pubmed-article:10921905 | pubmed:meshHeading | pubmed-meshheading:10921905... | lld:pubmed |
| pubmed-article:10921905 | pubmed:meshHeading | pubmed-meshheading:10921905... | lld:pubmed |
| pubmed-article:10921905 | pubmed:meshHeading | pubmed-meshheading:10921905... | lld:pubmed |
| pubmed-article:10921905 | pubmed:meshHeading | pubmed-meshheading:10921905... | lld:pubmed |
| pubmed-article:10921905 | pubmed:meshHeading | pubmed-meshheading:10921905... | lld:pubmed |
| pubmed-article:10921905 | pubmed:meshHeading | pubmed-meshheading:10921905... | lld:pubmed |
| pubmed-article:10921905 | pubmed:meshHeading | pubmed-meshheading:10921905... | lld:pubmed |
| pubmed-article:10921905 | pubmed:meshHeading | pubmed-meshheading:10921905... | lld:pubmed |
| pubmed-article:10921905 | pubmed:meshHeading | pubmed-meshheading:10921905... | lld:pubmed |
| pubmed-article:10921905 | pubmed:meshHeading | pubmed-meshheading:10921905... | lld:pubmed |
| pubmed-article:10921905 | pubmed:meshHeading | pubmed-meshheading:10921905... | lld:pubmed |
| pubmed-article:10921905 | pubmed:meshHeading | pubmed-meshheading:10921905... | lld:pubmed |
| pubmed-article:10921905 | pubmed:meshHeading | pubmed-meshheading:10921905... | lld:pubmed |
| pubmed-article:10921905 | pubmed:meshHeading | pubmed-meshheading:10921905... | lld:pubmed |
| pubmed-article:10921905 | pubmed:year | 2000 | lld:pubmed |
| pubmed-article:10921905 | pubmed:articleTitle | A transcriptional insulator at the imprinted H19/Igf2 locus. | lld:pubmed |
