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pubmed-article:10913390pubmed:abstractTextCurrent evidence suggests that controlling antibiotic resistance requires the monitoring of both susceptibility trends and antimicrobial usage within specific patient-care areas of the hospital. To assess the differences between antimicrobial usage-versus-susceptibility relationships found in the hospital and those relationships found in specific patient-care areas, susceptibility and antimicrobial usage data collected over a 5-year period (1992-1996) at the Medical University of South Carolina were analyzed. For each area, the relationship between drug use and susceptibility was analyzed for 8 gram-negative organisms with respect to 19 different agents and for 3 staphylococci with respect to 10 agents with use of simple linear regression. The relationships found in the hospital had a poorer overall agreement with the relationships found in the intensive care units (ICUs; <20%) than they did with the relationships found in the non-ICUs ( approximately 65%). Surveillance should include both susceptibility and drug usage patterns in individual areas within an institution.lld:pubmed
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pubmed-article:10913390pubmed:authorpubmed-author:WhiteR LRLlld:pubmed
pubmed-article:10913390pubmed:authorpubmed-author:BossoJ AJAlld:pubmed
pubmed-article:10913390pubmed:authorpubmed-author:FriedrichL...lld:pubmed
pubmed-article:10913390pubmed:authorpubmed-author:MihmL BLBlld:pubmed
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pubmed-article:10913390pubmed:volume31lld:pubmed
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pubmed-article:10913390pubmed:pagination16-23lld:pubmed
pubmed-article:10913390pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:10913390pubmed:year2000lld:pubmed
pubmed-article:10913390pubmed:articleTitleAssessment of the relationship between antimicrobial usage and susceptibility: differences between the hospital and specific patient-care areas.lld:pubmed
pubmed-article:10913390pubmed:affiliationMedical University of South Carolina, College of Pharmacy, Anti-Infective Research Laboratory, Charleston, SC, 29425, USA. whiterl@musc.edulld:pubmed
pubmed-article:10913390pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:10913390pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed