| pubmed-article:10910427 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10910427 | lifeskim:mentions | umls-concept:C0011570 | lld:lifeskim |
| pubmed-article:10910427 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:10910427 | pubmed:dateCreated | 2000-8-23 | lld:pubmed |
| pubmed-article:10910427 | pubmed:abstractText | The authors conducted a follow-up study of 16 patients with late-life depression approximately 6 years after their initial assessment to evaluate the relationships between apolipoprotein-E (APO-E) status and white-matter hyperintensities (WMH). Ten patients had WMH at baseline, and four patients demonstrated an increase in WMH size over time. Three of four patients with the APO-E epsilon 4 allele demonstrated an increase in WMH over time, and only 1 of 12 patients without an epsilon 4 allele had an increase in WMH. Three of four patients with APO-E epsilon 4 allele developed a chronic course of major depression at follow-up. Patients with APO-E epsilon 4 had a higher number of depressive episodes and lower age at onset. APO-E may be a risk factor for cerebrovascular disease associated with late-life depression and may affect the clinical characteristics and disease course of depression. | lld:pubmed |
| pubmed-article:10910427 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10910427 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10910427 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10910427 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10910427 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10910427 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10910427 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10910427 | pubmed:issn | 1064-7481 | lld:pubmed |
| pubmed-article:10910427 | pubmed:author | pubmed-author:MillerB LBL | lld:pubmed |
| pubmed-article:10910427 | pubmed:author | pubmed-author:MehringerC... | lld:pubmed |
| pubmed-article:10910427 | pubmed:author | pubmed-author:LesserI MIM | lld:pubmed |
| pubmed-article:10910427 | pubmed:author | pubmed-author:VintersH VHV | lld:pubmed |
| pubmed-article:10910427 | pubmed:author | pubmed-author:WohlMM | lld:pubmed |
| pubmed-article:10910427 | pubmed:author | pubmed-author:LavretskyHH | lld:pubmed |
| pubmed-article:10910427 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10910427 | pubmed:volume | 8 | lld:pubmed |
| pubmed-article:10910427 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10910427 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10910427 | pubmed:pagination | 257-61 | lld:pubmed |
| pubmed-article:10910427 | pubmed:dateRevised | 2011-9-22 | lld:pubmed |
| pubmed-article:10910427 | pubmed:meshHeading | pubmed-meshheading:10910427... | lld:pubmed |
| pubmed-article:10910427 | pubmed:meshHeading | pubmed-meshheading:10910427... | lld:pubmed |
| pubmed-article:10910427 | pubmed:meshHeading | pubmed-meshheading:10910427... | lld:pubmed |
| pubmed-article:10910427 | pubmed:meshHeading | pubmed-meshheading:10910427... | lld:pubmed |
| pubmed-article:10910427 | pubmed:meshHeading | pubmed-meshheading:10910427... | lld:pubmed |
| pubmed-article:10910427 | pubmed:meshHeading | pubmed-meshheading:10910427... | lld:pubmed |
| pubmed-article:10910427 | pubmed:meshHeading | pubmed-meshheading:10910427... | lld:pubmed |
| pubmed-article:10910427 | pubmed:meshHeading | pubmed-meshheading:10910427... | lld:pubmed |
| pubmed-article:10910427 | pubmed:meshHeading | pubmed-meshheading:10910427... | lld:pubmed |
| pubmed-article:10910427 | pubmed:meshHeading | pubmed-meshheading:10910427... | lld:pubmed |
| pubmed-article:10910427 | pubmed:meshHeading | pubmed-meshheading:10910427... | lld:pubmed |
| pubmed-article:10910427 | pubmed:meshHeading | pubmed-meshheading:10910427... | lld:pubmed |
| pubmed-article:10910427 | pubmed:meshHeading | pubmed-meshheading:10910427... | lld:pubmed |
| pubmed-article:10910427 | pubmed:meshHeading | pubmed-meshheading:10910427... | lld:pubmed |
| pubmed-article:10910427 | pubmed:year | 2000 | lld:pubmed |
| pubmed-article:10910427 | pubmed:articleTitle | Apolipoprotein-E and white-matter hyperintensities in late-life depression. | lld:pubmed |
| pubmed-article:10910427 | pubmed:affiliation | Department of Psychiatry, UCLA School of Medicine, Los Angeles, CA, USA. | lld:pubmed |
| pubmed-article:10910427 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10910427 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10910427 | lld:pubmed |
