Chronic liver diseases can progress to cirrhosis and to hepatocellular carcinoma. Timely and unequivocal recognition of the neoplastic evolution of cirrhosis is critical. To this aim, we used a noncompetitive reverse transcription-PCR procedure to analyze aldolase A mRNA in liver tissue from patients with chronic liver diseases at different stages.
Dipartimento di Biochimica e Biotecnologie Mediche and CEINGE scarl, Cattedra di Gastroenterologia, Facoltà di Medicina e Chirurgia, Università di Napoli "Federico II", I-80131 Naples, Italy.
