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pubmed-article:10891144pubmed:abstractTextThe oxidative cyclization of a phenolic amide to a spirolactam has long been regarded as an "impossible" reaction, because exposure of the substrates to a variety of oxidants results in formation of spirolactones with consequent loss of the amine segment. We recently communicated that this heretofore unknown transformation may be achieved by oxidation of oxazoline analogues of phenolic and indolic amides. Herein, we provide full details of our work.lld:pubmed
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pubmed-article:10891144pubmed:dateRevised2007-11-14lld:pubmed
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pubmed-article:10891144pubmed:articleTitleNew oxidative transformations of phenolic and indolic oxazolines: an avenue to useful azaspirocyclic building blocks.lld:pubmed
pubmed-article:10891144pubmed:affiliationDepartment of Chemistry, MS 60, Rice University, Houston, TX 77005-1892, USA.lld:pubmed
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