| pubmed-article:10877522 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10877522 | lifeskim:mentions | umls-concept:C1516213 | lld:lifeskim |
| pubmed-article:10877522 | lifeskim:mentions | umls-concept:C0026473 | lld:lifeskim |
| pubmed-article:10877522 | lifeskim:mentions | umls-concept:C0065088 | lld:lifeskim |
| pubmed-article:10877522 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:10877522 | lifeskim:mentions | umls-concept:C1819442 | lld:lifeskim |
| pubmed-article:10877522 | lifeskim:mentions | umls-concept:C1533691 | lld:lifeskim |
| pubmed-article:10877522 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:10877522 | pubmed:dateCreated | 2000-10-12 | lld:pubmed |
| pubmed-article:10877522 | pubmed:abstractText | Lithium salt compounds are used to limit the degree and duration of neutropenia in patients receiving chemotherapy for cancer. Interleukin-15 (IL-15) is a cytokine which possesses promoting activities on hematopoiesis and is also involved in antitumor response, activating NK, CTL and LAK cells. In this study we analyzed IL-15 production by monocyte cultures treated with lithium chloride (LiCl). Monocytes were obtained from patients affected by non-metastatic and metastatic breast cancer. LiCl treatment induced IL-15 production by monocytes mainly from non-metastatic patients. Combined lipopolysaccharide/LiCl treatment of monocyte cultures up-regulated IL-15 release compared to those treated with LPS alone (p<0.0001). The modulation of LiCl-induced IL-15 could counteract the immunosuppression state of cancer patients, which should be taken into account when developing new immunotherapeutic strategies. | lld:pubmed |
| pubmed-article:10877522 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10877522 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10877522 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10877522 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10877522 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10877522 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10877522 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10877522 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:10877522 | pubmed:issn | 1120-009X | lld:pubmed |
| pubmed-article:10877522 | pubmed:author | pubmed-author:ValentiAA | lld:pubmed |
| pubmed-article:10877522 | pubmed:author | pubmed-author:BenaMM | lld:pubmed |
| pubmed-article:10877522 | pubmed:author | pubmed-author:ArenaAA | lld:pubmed |
| pubmed-article:10877522 | pubmed:author | pubmed-author:MerendinoR... | lld:pubmed |
| pubmed-article:10877522 | pubmed:author | pubmed-author:LosaMM | lld:pubmed |
| pubmed-article:10877522 | pubmed:author | pubmed-author:D'AmbrosioF... | lld:pubmed |
| pubmed-article:10877522 | pubmed:author | pubmed-author:GangemiSS | lld:pubmed |
| pubmed-article:10877522 | pubmed:author | pubmed-author:RuelloAA | lld:pubmed |
| pubmed-article:10877522 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10877522 | pubmed:volume | 12 | lld:pubmed |
| pubmed-article:10877522 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10877522 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10877522 | pubmed:pagination | 252-7 | lld:pubmed |
| pubmed-article:10877522 | pubmed:dateRevised | 2009-8-4 | lld:pubmed |
| pubmed-article:10877522 | pubmed:meshHeading | pubmed-meshheading:10877522... | lld:pubmed |
| pubmed-article:10877522 | pubmed:meshHeading | pubmed-meshheading:10877522... | lld:pubmed |
| pubmed-article:10877522 | pubmed:meshHeading | pubmed-meshheading:10877522... | lld:pubmed |
| pubmed-article:10877522 | pubmed:meshHeading | pubmed-meshheading:10877522... | lld:pubmed |
| pubmed-article:10877522 | pubmed:meshHeading | pubmed-meshheading:10877522... | lld:pubmed |
| pubmed-article:10877522 | pubmed:meshHeading | pubmed-meshheading:10877522... | lld:pubmed |
| pubmed-article:10877522 | pubmed:meshHeading | pubmed-meshheading:10877522... | lld:pubmed |
| pubmed-article:10877522 | pubmed:meshHeading | pubmed-meshheading:10877522... | lld:pubmed |
| pubmed-article:10877522 | pubmed:meshHeading | pubmed-meshheading:10877522... | lld:pubmed |
| pubmed-article:10877522 | pubmed:meshHeading | pubmed-meshheading:10877522... | lld:pubmed |
| pubmed-article:10877522 | pubmed:meshHeading | pubmed-meshheading:10877522... | lld:pubmed |
| pubmed-article:10877522 | pubmed:year | 2000 | lld:pubmed |
| pubmed-article:10877522 | pubmed:articleTitle | In vitro effect of lithium chloride on interleukin-15 production by monocytes from IL-breast cancer patients. | lld:pubmed |
| pubmed-article:10877522 | pubmed:affiliation | Immunopathology, Institute of Medical Pathology and Mediterranean Medicine, University of Messina Medical School, Italy. | lld:pubmed |
| pubmed-article:10877522 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:10877522 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:10877522 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
