pubmed-article:1087292 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:1087292 | lifeskim:mentions | umls-concept:C0085080 | lld:lifeskim |
pubmed-article:1087292 | lifeskim:mentions | umls-concept:C0007620 | lld:lifeskim |
pubmed-article:1087292 | lifeskim:mentions | umls-concept:C0032207 | lld:lifeskim |
pubmed-article:1087292 | lifeskim:mentions | umls-concept:C1704675 | lld:lifeskim |
pubmed-article:1087292 | lifeskim:mentions | umls-concept:C0851346 | lld:lifeskim |
pubmed-article:1087292 | lifeskim:mentions | umls-concept:C1521991 | lld:lifeskim |
pubmed-article:1087292 | lifeskim:mentions | umls-concept:C0439855 | lld:lifeskim |
pubmed-article:1087292 | lifeskim:mentions | umls-concept:C0936012 | lld:lifeskim |
pubmed-article:1087292 | lifeskim:mentions | umls-concept:C0871935 | lld:lifeskim |
pubmed-article:1087292 | pubmed:issue | 6 | lld:pubmed |
pubmed-article:1087292 | pubmed:dateCreated | 1977-2-24 | lld:pubmed |
pubmed-article:1087292 | pubmed:abstractText | A mathematical analysis is developed from the concepts of the molecular theory of cell survival to explain the cytotoxic action of a platinum complex on CHO cells and its synergistic interaction with radiation. In the analysis, it is assumed that both inter- and intra-strand cross-links induced by the Pt complex in the DNA contribute to cell killing and that the synergistic effect arises from the interaction between an intra-strand cross-link and a radiation-induced single-strand break on complementary strands of the DNA. The analysis is shown to be compatible with experimental results. Further, a mechanistic model is developed in an attempt to explain in more detail the processes which appear to be involved in the expression of the cytological damage. | lld:pubmed |
pubmed-article:1087292 | pubmed:language | eng | lld:pubmed |
pubmed-article:1087292 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1087292 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:1087292 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1087292 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1087292 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1087292 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:1087292 | pubmed:month | Dec | lld:pubmed |
pubmed-article:1087292 | pubmed:issn | 0020-7616 | lld:pubmed |
pubmed-article:1087292 | pubmed:author | pubmed-author:NiasA HAH | lld:pubmed |
pubmed-article:1087292 | pubmed:author | pubmed-author:SzumielII | lld:pubmed |
pubmed-article:1087292 | pubmed:author | pubmed-author:ChadwickK HKH | lld:pubmed |
pubmed-article:1087292 | pubmed:author | pubmed-author:LeenhoutsH... | lld:pubmed |
pubmed-article:1087292 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:1087292 | pubmed:volume | 30 | lld:pubmed |
pubmed-article:1087292 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:1087292 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:1087292 | pubmed:pagination | 511-24 | lld:pubmed |
pubmed-article:1087292 | pubmed:dateRevised | 2000-12-18 | lld:pubmed |
pubmed-article:1087292 | pubmed:meshHeading | pubmed-meshheading:1087292-... | lld:pubmed |
pubmed-article:1087292 | pubmed:meshHeading | pubmed-meshheading:1087292-... | lld:pubmed |
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pubmed-article:1087292 | pubmed:meshHeading | pubmed-meshheading:1087292-... | lld:pubmed |
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pubmed-article:1087292 | pubmed:meshHeading | pubmed-meshheading:1087292-... | lld:pubmed |
pubmed-article:1087292 | pubmed:meshHeading | pubmed-meshheading:1087292-... | lld:pubmed |
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pubmed-article:1087292 | pubmed:meshHeading | pubmed-meshheading:1087292-... | lld:pubmed |
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pubmed-article:1087292 | pubmed:meshHeading | pubmed-meshheading:1087292-... | lld:pubmed |
pubmed-article:1087292 | pubmed:year | 1976 | lld:pubmed |
pubmed-article:1087292 | pubmed:articleTitle | An analysis of the interaction of a platinum complex and radiation with CHO cells using the molecular theory of cell survival. | lld:pubmed |
pubmed-article:1087292 | pubmed:publicationType | Journal Article | lld:pubmed |
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