pubmed-article:10859386 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:10859386 | lifeskim:mentions | umls-concept:C0014644 | lld:lifeskim |
pubmed-article:10859386 | lifeskim:mentions | umls-concept:C1049553 | lld:lifeskim |
pubmed-article:10859386 | lifeskim:mentions | umls-concept:C0162638 | lld:lifeskim |
pubmed-article:10859386 | lifeskim:mentions | umls-concept:C0205245 | lld:lifeskim |
pubmed-article:10859386 | lifeskim:mentions | umls-concept:C2700640 | lld:lifeskim |
pubmed-article:10859386 | lifeskim:mentions | umls-concept:C1334043 | lld:lifeskim |
pubmed-article:10859386 | lifeskim:mentions | umls-concept:C2003905 | lld:lifeskim |
pubmed-article:10859386 | pubmed:issue | Pt 7 | lld:pubmed |
pubmed-article:10859386 | pubmed:dateCreated | 2000-7-27 | lld:pubmed |
pubmed-article:10859386 | pubmed:abstractText | The human tumour virus Epstein-Barr virus (EBV) encodes a 17 kDa protein, BHRF1, which is a member of the BCL:-2 family and has been shown to suppress apoptosis. The role of this gene in the life-cycle of EBV has not been fully elucidated. In order to identify motifs conserved in herpesviruses and possibly shed light on its function we isolated a BHRF1 homologue from herpesvirus papio (cercopithecine herpesvirus-12) a closely related gammaherpesvirus of baboons. The gene, hvpBHRF1, also encodes a 17 kDa protein which shares 64% identity and 79% similarity with EBV BHRF1 at the amino acid level. In biological assays, hvpBHRF1 and BHRF1 conferred similar levels of protection on human keratinocytes induced to apoptose with cis-platin. | lld:pubmed |
pubmed-article:10859386 | pubmed:language | eng | lld:pubmed |
pubmed-article:10859386 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:10859386 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:10859386 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:10859386 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:10859386 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:10859386 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:10859386 | pubmed:month | Jul | lld:pubmed |
pubmed-article:10859386 | pubmed:issn | 0022-1317 | lld:pubmed |
pubmed-article:10859386 | pubmed:author | pubmed-author:ArrandJ RJR | lld:pubmed |
pubmed-article:10859386 | pubmed:author | pubmed-author:MackettMM | lld:pubmed |
pubmed-article:10859386 | pubmed:author | pubmed-author:MesedaC ACA | lld:pubmed |
pubmed-article:10859386 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:10859386 | pubmed:volume | 81 | lld:pubmed |
pubmed-article:10859386 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:10859386 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:10859386 | pubmed:pagination | 1801-5 | lld:pubmed |
pubmed-article:10859386 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
pubmed-article:10859386 | pubmed:meshHeading | pubmed-meshheading:10859386... | lld:pubmed |
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pubmed-article:10859386 | pubmed:meshHeading | pubmed-meshheading:10859386... | lld:pubmed |
pubmed-article:10859386 | pubmed:year | 2000 | lld:pubmed |
pubmed-article:10859386 | pubmed:articleTitle | Herpesvirus papio encodes a functional homologue of the Epstein-Barr virus apoptosis suppressor, BHRF1. | lld:pubmed |
pubmed-article:10859386 | pubmed:affiliation | Department of Molecular Biology, Paterson Institute for Cancer Research, Christie Hospital NHS Trust, Wilmslow Road, Withington, Manchester M20 9BX, UK. | lld:pubmed |
pubmed-article:10859386 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:10859386 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10859386 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10859386 | lld:pubmed |