| pubmed-article:10841040 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10841040 | lifeskim:mentions | umls-concept:C0042037 | lld:lifeskim |
| pubmed-article:10841040 | lifeskim:mentions | umls-concept:C0001128 | lld:lifeskim |
| pubmed-article:10841040 | lifeskim:mentions | umls-concept:C0022023 | lld:lifeskim |
| pubmed-article:10841040 | lifeskim:mentions | umls-concept:C0680730 | lld:lifeskim |
| pubmed-article:10841040 | lifeskim:mentions | umls-concept:C0205160 | lld:lifeskim |
| pubmed-article:10841040 | lifeskim:mentions | umls-concept:C1996904 | lld:lifeskim |
| pubmed-article:10841040 | lifeskim:mentions | umls-concept:C0812407 | lld:lifeskim |
| pubmed-article:10841040 | lifeskim:mentions | umls-concept:C0008555 | lld:lifeskim |
| pubmed-article:10841040 | lifeskim:mentions | umls-concept:C1880497 | lld:lifeskim |
| pubmed-article:10841040 | lifeskim:mentions | umls-concept:C1148554 | lld:lifeskim |
| pubmed-article:10841040 | lifeskim:mentions | umls-concept:C0260255 | lld:lifeskim |
| pubmed-article:10841040 | lifeskim:mentions | umls-concept:C0046616 | lld:lifeskim |
| pubmed-article:10841040 | lifeskim:mentions | umls-concept:C0522529 | lld:lifeskim |
| pubmed-article:10841040 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:10841040 | pubmed:dateCreated | 2000-9-20 | lld:pubmed |
| pubmed-article:10841040 | pubmed:abstractText | 20-Hydroxy-arachidonic acid (20-HETE) was determined in urine by an isotope dilution assay using gas chromatography/mass spectrometry (GC/MS). After addition of 18O2-internal standard, 20-HETE was extracted from urine with hexane either directly or after treatment with glucuronidase. 20-HETE was derivatized to the pentafluorobenzylester and the sample was applied to thin layer chromatography with iso-octane/iso-propanol 9:1 (v/v) as the developing solvent. The corresponding zone was extracted and 20-HETE was hydrogenated. After derivatization to the trimethylsilylether, 20-HETE was determined by GC/MS using the [M-pentafluorobenzyl]- -ion in the negative ion chemical ionization mode. Excretion rates of free and glucuronide conjugated 20-HETE was determined in healthy children and in children with hyperprostaglandin-E-syndrome/antenatal Bartter syndrome (HPS/aBS) with or without indomethacin treatment. Compared to the controls, the HPS/aBS children showed higher excretion rates of 20-HETE, which were suppressed to normal values under indomethacin medication. Free and glucuronide conjugated 20-HETE do not correlate with PGE2 excluding any participation in HPS/aBS. | lld:pubmed |
| pubmed-article:10841040 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10841040 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10841040 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10841040 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10841040 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10841040 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10841040 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10841040 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10841040 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10841040 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10841040 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:10841040 | pubmed:issn | 0952-3278 | lld:pubmed |
| pubmed-article:10841040 | pubmed:author | pubmed-author:SeyberthH WHW | lld:pubmed |
| pubmed-article:10841040 | pubmed:author | pubmed-author:SchweerHH | lld:pubmed |
| pubmed-article:10841040 | pubmed:author | pubmed-author:RützelHH | lld:pubmed |
| pubmed-article:10841040 | pubmed:author | pubmed-author:ReinalterSS | lld:pubmed |
| pubmed-article:10841040 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10841040 | pubmed:volume | 62 | lld:pubmed |
| pubmed-article:10841040 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10841040 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10841040 | pubmed:pagination | 175-81 | lld:pubmed |
| pubmed-article:10841040 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:10841040 | pubmed:meshHeading | pubmed-meshheading:10841040... | lld:pubmed |
| pubmed-article:10841040 | pubmed:meshHeading | pubmed-meshheading:10841040... | lld:pubmed |
| pubmed-article:10841040 | pubmed:meshHeading | pubmed-meshheading:10841040... | lld:pubmed |
| pubmed-article:10841040 | pubmed:meshHeading | pubmed-meshheading:10841040... | lld:pubmed |
| pubmed-article:10841040 | pubmed:meshHeading | pubmed-meshheading:10841040... | lld:pubmed |
| pubmed-article:10841040 | pubmed:meshHeading | pubmed-meshheading:10841040... | lld:pubmed |
| pubmed-article:10841040 | pubmed:meshHeading | pubmed-meshheading:10841040... | lld:pubmed |
| pubmed-article:10841040 | pubmed:meshHeading | pubmed-meshheading:10841040... | lld:pubmed |
| pubmed-article:10841040 | pubmed:meshHeading | pubmed-meshheading:10841040... | lld:pubmed |
| pubmed-article:10841040 | pubmed:meshHeading | pubmed-meshheading:10841040... | lld:pubmed |
| pubmed-article:10841040 | pubmed:meshHeading | pubmed-meshheading:10841040... | lld:pubmed |
| pubmed-article:10841040 | pubmed:meshHeading | pubmed-meshheading:10841040... | lld:pubmed |
| pubmed-article:10841040 | pubmed:meshHeading | pubmed-meshheading:10841040... | lld:pubmed |
| pubmed-article:10841040 | pubmed:year | 2000 | lld:pubmed |
| pubmed-article:10841040 | pubmed:articleTitle | Determination of free and glucuronide conjugated 20-hydroxyarachidonic acid (20-HETE) in urine by gas chromatography/negative ion chemical ionization mass spectrometry. | lld:pubmed |
| pubmed-article:10841040 | pubmed:affiliation | Department of Pediatrics, Philipps University Marburg, Germany. | lld:pubmed |
| pubmed-article:10841040 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:10841040 | pubmed:publicationType | Comparative Study | lld:pubmed |
