Linked Life Data

10831941

Source:http://linkedlifedata.com/resource/pubmed/id/10831941

Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:10831941rdf:typepubmed:Citationlld:pubmed
pubmed-article:10831941lifeskim:mentionsumls-concept:C0030705lld:lifeskim
pubmed-article:10831941lifeskim:mentionsumls-concept:C0011849lld:lifeskim
pubmed-article:10831941lifeskim:mentionsumls-concept:C0026473lld:lifeskim
pubmed-article:10831941lifeskim:mentionsumls-concept:C0852949lld:lifeskim
pubmed-article:10831941lifeskim:mentionsumls-concept:C1367477lld:lifeskim
pubmed-article:10831941lifeskim:mentionsumls-concept:C0205217lld:lifeskim
pubmed-article:10831941lifeskim:mentionsumls-concept:C0017262lld:lifeskim
pubmed-article:10831941lifeskim:mentionsumls-concept:C0175630lld:lifeskim
pubmed-article:10831941lifeskim:mentionsumls-concept:C2911684lld:lifeskim
pubmed-article:10831941lifeskim:mentionsumls-concept:C0185117lld:lifeskim
pubmed-article:10831941pubmed:issue11lld:pubmed
pubmed-article:10831941pubmed:dateCreated2000-7-11lld:pubmed
pubmed-article:10831941pubmed:abstractTextLow serum concentrations of high-density lipoprotein (HDL) cholesterol and elevated levels of acute-phase reactans are frequently found in patients with non-insulin-dependent diabetes mellitus (NIDDM) and cardiovascular disease. Changes in the phenotype of circulating monocytes have been reported with both of these circumstances in nondiabetic subjects. In the present study, we explored the possibility that similar changes may occur in circulating monocytes of patients with NIDDM and arterial disease. Two groups of subjects with NIDDM were studied: patients with cardiovascular disease (n = 25) were compared with a group without cardiovascular disease (n = 26); both groups were age- and sex-matched, had the same length of diabetes duration, and degree of glycemic control. Healthy nondiabetic volunteers of comparable age and sex (n = 35) formed the control group. There was no significant difference in the numbers of the CD14+/CD16+ monocyte subpopulations between the 3 groups. However, a significant graded increase of the mCD14 intensity expression values was observed among the groups, with the highest levels in patients with NIDDM patients and the lowest in nondiabetic subjects. The serum C-reactive protein concentrations were significantly higher in the group with arterial disease compared with those without arterial disease or healthy controls. In the group of patients as a whole, relative mCD14 intensity expression was significantly correlated with HDL cholesterol levels (inversely) and with serum concentrations of C-reactive protein. Serum HDL cholesterol levels and the C-reactive protein concentrations were also significantly correlated. We concluded that the increased mCD14 intensity expression on circulating monocytes may be an important contributor to the increased inflammatory response observed in patients with NIDDM and arterial disease, and eventually, to atherogenesis.lld:pubmed
pubmed-article:10831941pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:10831941pubmed:languageenglld:pubmed
pubmed-article:10831941pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:10831941pubmed:citationSubsetAIMlld:pubmed
pubmed-article:10831941pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:10831941pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:10831941pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:10831941pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:10831941pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:10831941pubmed:statusMEDLINElld:pubmed
pubmed-article:10831941pubmed:monthJunlld:pubmed
pubmed-article:10831941pubmed:issn0002-9149lld:pubmed
pubmed-article:10831941pubmed:authorpubmed-author:RodriguezAAlld:pubmed
pubmed-article:10831941pubmed:authorpubmed-author:FigueredoAAlld:pubmed
pubmed-article:10831941pubmed:authorpubmed-author:PatiñoRRlld:pubmed
pubmed-article:10831941pubmed:authorpubmed-author:IbarraJJlld:pubmed
pubmed-article:10831941pubmed:authorpubmed-author:Fernandez-Cru...lld:pubmed
pubmed-article:10831941pubmed:authorpubmed-author:PintorEElld:pubmed
pubmed-article:10831941pubmed:authorpubmed-author:YagüeM RMRlld:pubmed
pubmed-article:10831941pubmed:issnTypePrintlld:pubmed
pubmed-article:10831941pubmed:day1lld:pubmed
pubmed-article:10831941pubmed:volume85lld:pubmed
pubmed-article:10831941pubmed:ownerNLMlld:pubmed
pubmed-article:10831941pubmed:authorsCompleteYlld:pubmed
pubmed-article:10831941pubmed:pagination1288-91lld:pubmed
pubmed-article:10831941pubmed:dateRevised2006-11-15lld:pubmed
pubmed-article:10831941pubmed:meshHeadingpubmed-meshheading:10831941...lld:pubmed
pubmed-article:10831941pubmed:meshHeadingpubmed-meshheading:10831941...lld:pubmed
pubmed-article:10831941pubmed:meshHeadingpubmed-meshheading:10831941...lld:pubmed
pubmed-article:10831941pubmed:meshHeadingpubmed-meshheading:10831941...lld:pubmed
pubmed-article:10831941pubmed:meshHeadingpubmed-meshheading:10831941...lld:pubmed
pubmed-article:10831941pubmed:meshHeadingpubmed-meshheading:10831941...lld:pubmed
pubmed-article:10831941pubmed:meshHeadingpubmed-meshheading:10831941...lld:pubmed
pubmed-article:10831941pubmed:meshHeadingpubmed-meshheading:10831941...lld:pubmed
pubmed-article:10831941pubmed:meshHeadingpubmed-meshheading:10831941...lld:pubmed
pubmed-article:10831941pubmed:meshHeadingpubmed-meshheading:10831941...lld:pubmed
pubmed-article:10831941pubmed:meshHeadingpubmed-meshheading:10831941...lld:pubmed
pubmed-article:10831941pubmed:meshHeadingpubmed-meshheading:10831941...lld:pubmed
pubmed-article:10831941pubmed:meshHeadingpubmed-meshheading:10831941...lld:pubmed
pubmed-article:10831941pubmed:meshHeadingpubmed-meshheading:10831941...lld:pubmed
pubmed-article:10831941pubmed:meshHeadingpubmed-meshheading:10831941...lld:pubmed
pubmed-article:10831941pubmed:meshHeadingpubmed-meshheading:10831941...lld:pubmed
pubmed-article:10831941pubmed:meshHeadingpubmed-meshheading:10831941...lld:pubmed
pubmed-article:10831941pubmed:year2000lld:pubmed
pubmed-article:10831941pubmed:articleTitleCirculating monocytes in patients with diabetes mellitus, arterial disease, and increased CD14 expression.lld:pubmed
pubmed-article:10831941pubmed:affiliationService of Internal Medicine III, Hospital Clìnico Universitario de San Carlos, Medicina III, Madrid, Spain.lld:pubmed
pubmed-article:10831941pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:10831941pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
entrez-gene:60350entrezgene:pubmedpubmed-article:10831941lld:entrezgene
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:10831941lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:10831941lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:10831941lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:10831941lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:10831941lld:pubmed