pubmed-article:10828710 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:10828710 | lifeskim:mentions | umls-concept:C0042136 | lld:lifeskim |
pubmed-article:10828710 | lifeskim:mentions | umls-concept:C0028736 | lld:lifeskim |
pubmed-article:10828710 | lifeskim:mentions | umls-concept:C0392756 | lld:lifeskim |
pubmed-article:10828710 | lifeskim:mentions | umls-concept:C1524063 | lld:lifeskim |
pubmed-article:10828710 | pubmed:issue | 4 | lld:pubmed |
pubmed-article:10828710 | pubmed:dateCreated | 2000-8-11 | lld:pubmed |
pubmed-article:10828710 | pubmed:abstractText | Implantation of intrauterine devices (IUDs) is associated with an increased incidence of uterine infection, probably as a result of vaginal bacteria entering the uterus at the time of insertion. To reduce the incidence of IUD-related infections, the incorporation of antimicrobial agents into the tail of the device was studied. Chlorhexidine was shown to be released from within nylon hollow fibres at a rate of approximately 114 microg x day(-1) for 10 days. This rate of release was sufficient to exhibit a biocidal effect on bacteria embedded within a mucus gel in vitro. When these devices were implanted transcervically into the guinea-pig uterus they significantly reduced the extent of uterine bacterial contamination within 24 h. These findings indicate that chlorhexidine-releasing devices are potentially useful in the reduction of device-related infections. | lld:pubmed |
pubmed-article:10828710 | pubmed:language | eng | lld:pubmed |
pubmed-article:10828710 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:10828710 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:10828710 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:10828710 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:10828710 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:10828710 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:10828710 | pubmed:issn | 0378-7346 | lld:pubmed |
pubmed-article:10828710 | pubmed:author | pubmed-author:HanlonG WGW | lld:pubmed |
pubmed-article:10828710 | pubmed:author | pubmed-author:GrayG FGF | lld:pubmed |
pubmed-article:10828710 | pubmed:author | pubmed-author:ReynoldsJ PJP | lld:pubmed |
pubmed-article:10828710 | pubmed:copyrightInfo | Copyright 2000 S. Karger AG, Basel | lld:pubmed |
pubmed-article:10828710 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:10828710 | pubmed:volume | 49 | lld:pubmed |
pubmed-article:10828710 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:10828710 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:10828710 | pubmed:pagination | 261-5 | lld:pubmed |
pubmed-article:10828710 | pubmed:dateRevised | 2004-11-17 | lld:pubmed |
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pubmed-article:10828710 | pubmed:year | 2000 | lld:pubmed |
pubmed-article:10828710 | pubmed:articleTitle | Use of chlorhexidine-releasing nylon fibres to reduce device-related uterine infections. | lld:pubmed |
pubmed-article:10828710 | pubmed:affiliation | School of Pharmacy and Biomolecular Sciences, University of Brighton, UK. p.r.gard@brighton.ac.uk | lld:pubmed |
pubmed-article:10828710 | pubmed:publicationType | Journal Article | lld:pubmed |