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pubmed-article:10825975pubmed:abstractText[formula: see text] The kinetic resolution of epoxides with phenols catalyzed by a polymer-supported Co(salen) complex is applied to the first enantioselective catalytic synthesis of parallel libraries. The corresponding 1-aryloxy-2-alcohols are obtained in high yield, purity, and enantiomeric excess. Further elaboration with diversity elements provides highly efficient access to important classes of pharmacologically active compounds.lld:pubmed
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pubmed-article:10825975pubmed:authorpubmed-author:JacobsenE NENlld:pubmed
pubmed-article:10825975pubmed:authorpubmed-author:PeukertSSlld:pubmed
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pubmed-article:10825975pubmed:dateRevised2007-11-14lld:pubmed
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pubmed-article:10825975pubmed:articleTitleEnantioselective parallel synthesis using polymer-supported chiral Co(salen) complexes.lld:pubmed
pubmed-article:10825975pubmed:affiliationDepartment of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, USA.lld:pubmed
pubmed-article:10825975pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:10825975pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
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