| pubmed-article:10821119 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10821119 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:10821119 | lifeskim:mentions | umls-concept:C0000097 | lld:lifeskim |
| pubmed-article:10821119 | lifeskim:mentions | umls-concept:C0018546 | lld:lifeskim |
| pubmed-article:10821119 | lifeskim:mentions | umls-concept:C0311400 | lld:lifeskim |
| pubmed-article:10821119 | lifeskim:mentions | umls-concept:C1314792 | lld:lifeskim |
| pubmed-article:10821119 | lifeskim:mentions | umls-concept:C1419114 | lld:lifeskim |
| pubmed-article:10821119 | lifeskim:mentions | umls-concept:C0243071 | lld:lifeskim |
| pubmed-article:10821119 | lifeskim:mentions | umls-concept:C0243067 | lld:lifeskim |
| pubmed-article:10821119 | pubmed:issue | 20 | lld:pubmed |
| pubmed-article:10821119 | pubmed:dateCreated | 2000-6-1 | lld:pubmed |
| pubmed-article:10821119 | pubmed:abstractText | The results of previous studies in the baboon have suggested that HPTP, the tetrahydropyridinyl analog of haloperidol causes a urinary biochemical marker profile similar to those seen in humans suffering from inborn errors of mitochondrial respiration. In order to identify a possible relationship between compromised cellular energy production and neuronal damage we now have compared the urinary profiles of rats treated with the pro-neurotoxin, MPTP as well as with HPTP. Significantly increased urinary excretion of lactic acid and 2-ethylhydracrylic acid in MPTP and HPTP treated rats was observed, indicating that both MPTP and HPTP and/or their respective metabolites cause mitochondrial inhibition in the rat. | lld:pubmed |
| pubmed-article:10821119 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10821119 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10821119 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10821119 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10821119 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10821119 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10821119 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10821119 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10821119 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10821119 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10821119 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10821119 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10821119 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:10821119 | pubmed:issn | 0024-3205 | lld:pubmed |
| pubmed-article:10821119 | pubmed:author | pubmed-author:CastagnoliNNJ... | lld:pubmed |
| pubmed-article:10821119 | pubmed:author | pubmed-author:BerghJ JJJ | lld:pubmed |
| pubmed-article:10821119 | pubmed:author | pubmed-author:Van der... | lld:pubmed |
| pubmed-article:10821119 | pubmed:author | pubmed-author:MienieL JLJ | lld:pubmed |
| pubmed-article:10821119 | pubmed:author | pubmed-author:PetzerJ PJP | lld:pubmed |
| pubmed-article:10821119 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10821119 | pubmed:day | 7 | lld:pubmed |
| pubmed-article:10821119 | pubmed:volume | 66 | lld:pubmed |
| pubmed-article:10821119 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10821119 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10821119 | pubmed:pagination | 1949-54 | lld:pubmed |
| pubmed-article:10821119 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:10821119 | pubmed:meshHeading | pubmed-meshheading:10821119... | lld:pubmed |
| pubmed-article:10821119 | pubmed:meshHeading | pubmed-meshheading:10821119... | lld:pubmed |
| pubmed-article:10821119 | pubmed:meshHeading | pubmed-meshheading:10821119... | lld:pubmed |
| pubmed-article:10821119 | pubmed:meshHeading | pubmed-meshheading:10821119... | lld:pubmed |
| pubmed-article:10821119 | pubmed:meshHeading | pubmed-meshheading:10821119... | lld:pubmed |
| pubmed-article:10821119 | pubmed:meshHeading | pubmed-meshheading:10821119... | lld:pubmed |
| pubmed-article:10821119 | pubmed:meshHeading | pubmed-meshheading:10821119... | lld:pubmed |
| pubmed-article:10821119 | pubmed:meshHeading | pubmed-meshheading:10821119... | lld:pubmed |
| pubmed-article:10821119 | pubmed:meshHeading | pubmed-meshheading:10821119... | lld:pubmed |
| pubmed-article:10821119 | pubmed:meshHeading | pubmed-meshheading:10821119... | lld:pubmed |
| pubmed-article:10821119 | pubmed:meshHeading | pubmed-meshheading:10821119... | lld:pubmed |
| pubmed-article:10821119 | pubmed:meshHeading | pubmed-meshheading:10821119... | lld:pubmed |
| pubmed-article:10821119 | pubmed:year | 2000 | lld:pubmed |
| pubmed-article:10821119 | pubmed:articleTitle | Metabolic defects caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and by HPTP (the tetrahydropyridinyl analog of haloperidol), in rats. | lld:pubmed |
| pubmed-article:10821119 | pubmed:affiliation | Department of Pharmaceutical Chemistry, Potchefstroom University for Christian Higher Education, South Africa. | lld:pubmed |
| pubmed-article:10821119 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:10821119 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:10821119 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:10821119 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
