| pubmed-article:10808407 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10808407 | lifeskim:mentions | umls-concept:C0009148 | lld:lifeskim |
| pubmed-article:10808407 | lifeskim:mentions | umls-concept:C0220781 | lld:lifeskim |
| pubmed-article:10808407 | lifeskim:mentions | umls-concept:C0439851 | lld:lifeskim |
| pubmed-article:10808407 | lifeskim:mentions | umls-concept:C1883254 | lld:lifeskim |
| pubmed-article:10808407 | lifeskim:mentions | umls-concept:C0034760 | lld:lifeskim |
| pubmed-article:10808407 | lifeskim:mentions | umls-concept:C1158479 | lld:lifeskim |
| pubmed-article:10808407 | lifeskim:mentions | umls-concept:C1552596 | lld:lifeskim |
| pubmed-article:10808407 | lifeskim:mentions | umls-concept:C1947931 | lld:lifeskim |
| pubmed-article:10808407 | lifeskim:mentions | umls-concept:C0301869 | lld:lifeskim |
| pubmed-article:10808407 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:10808407 | pubmed:dateCreated | 2000-7-24 | lld:pubmed |
| pubmed-article:10808407 | pubmed:abstractText | The cobalt(II) tetracarboxyphthalocyanine-deoxyribonucleotide pd(TCTTCCCA) conjugate was synthesized. The phthalocyanine N-succinimide ester prepared from phthalocyanine using DCC was mixed in DMF with an aqueous solution of the oligonucleotide bearing a 1,3-diaminopropane linker at the 5'-phosphate. The resulting conjugate was tested in the intraduplex reaction with target 14-mer and 22-mer oligonucleotides containing conjugate-complementary sequences. In the presence of O2 and a thiol (2-mercaptoethanol or DTT) as a coupled reducer or H2O2, sequence-specific DNA modification was observed that caused the cleavage of the target upon treatment with piperidine. | lld:pubmed |
| pubmed-article:10808407 | pubmed:language | rus | lld:pubmed |
| pubmed-article:10808407 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10808407 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10808407 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10808407 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10808407 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10808407 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10808407 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10808407 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10808407 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:10808407 | pubmed:issn | 0132-3423 | lld:pubmed |
| pubmed-article:10808407 | pubmed:author | pubmed-author:KnorreD GDG | lld:pubmed |
| pubmed-article:10808407 | pubmed:author | pubmed-author:IvanovaT MTM | lld:pubmed |
| pubmed-article:10808407 | pubmed:author | pubmed-author:FedorovaO SOS | lld:pubmed |
| pubmed-article:10808407 | pubmed:author | pubmed-author:AbramovaT VTV | lld:pubmed |
| pubmed-article:10808407 | pubmed:author | pubmed-author:Koval'V VVV | lld:pubmed |
| pubmed-article:10808407 | pubmed:author | pubmed-author:ChernonosovA... | lld:pubmed |
| pubmed-article:10808407 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10808407 | pubmed:volume | 26 | lld:pubmed |
| pubmed-article:10808407 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10808407 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10808407 | pubmed:pagination | 118-25 | lld:pubmed |
| pubmed-article:10808407 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:10808407 | pubmed:meshHeading | pubmed-meshheading:10808407... | lld:pubmed |
| pubmed-article:10808407 | pubmed:meshHeading | pubmed-meshheading:10808407... | lld:pubmed |
| pubmed-article:10808407 | pubmed:meshHeading | pubmed-meshheading:10808407... | lld:pubmed |
| pubmed-article:10808407 | pubmed:meshHeading | pubmed-meshheading:10808407... | lld:pubmed |
| pubmed-article:10808407 | pubmed:meshHeading | pubmed-meshheading:10808407... | lld:pubmed |
| pubmed-article:10808407 | pubmed:meshHeading | pubmed-meshheading:10808407... | lld:pubmed |
| pubmed-article:10808407 | pubmed:year | 2000 | lld:pubmed |
| pubmed-article:10808407 | pubmed:articleTitle | [The synthesis of a cobalt(II) tetracarboxyphthalocyanine- deoxyribooligonucleotide conjugate as a reagent for the directed DNA modification]. | lld:pubmed |
| pubmed-article:10808407 | pubmed:affiliation | Novosibirsk Institute of Bioorganic Chemistry, Siberian Division, Russian Academy of Sciences, Russia. | lld:pubmed |
| pubmed-article:10808407 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:10808407 | pubmed:publicationType | English Abstract | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10808407 | lld:pubmed |
