pubmed-article:10795736 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:10795736 | lifeskim:mentions | umls-concept:C0026336 | lld:lifeskim |
pubmed-article:10795736 | lifeskim:mentions | umls-concept:C1332717 | lld:lifeskim |
pubmed-article:10795736 | lifeskim:mentions | umls-concept:C1706438 | lld:lifeskim |
pubmed-article:10795736 | lifeskim:mentions | umls-concept:C0814999 | lld:lifeskim |
pubmed-article:10795736 | lifeskim:mentions | umls-concept:C0085358 | lld:lifeskim |
pubmed-article:10795736 | lifeskim:mentions | umls-concept:C1332714 | lld:lifeskim |
pubmed-article:10795736 | lifeskim:mentions | umls-concept:C0036576 | lld:lifeskim |
pubmed-article:10795736 | lifeskim:mentions | umls-concept:C1413244 | lld:lifeskim |
pubmed-article:10795736 | lifeskim:mentions | umls-concept:C2698600 | lld:lifeskim |
pubmed-article:10795736 | lifeskim:mentions | umls-concept:C0183683 | lld:lifeskim |
pubmed-article:10795736 | lifeskim:mentions | umls-concept:C0205250 | lld:lifeskim |
pubmed-article:10795736 | lifeskim:mentions | umls-concept:C1881379 | lld:lifeskim |
pubmed-article:10795736 | pubmed:issue | 4 | lld:pubmed |
pubmed-article:10795736 | pubmed:dateCreated | 2000-5-23 | lld:pubmed |
pubmed-article:10795736 | pubmed:abstractText | We undertook a kinetic analysis of the generation of mature T cells in TCR and coreceptor transgenic mice using BrdU labeling. We observed that the selection efficiency of mature CD4-CD8+ and CD4+CD8- thymocytes could be as high as 40% and 90% of CD4+CD8+ precursors, respectively. The surprisingly high efficiency of selection favors an instructional model of lineage commitment and is incompatible with a stochastic model in which the efficiency of selection would be no greater than 100% in both lineages combined. | lld:pubmed |
pubmed-article:10795736 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:10795736 | pubmed:language | eng | lld:pubmed |
pubmed-article:10795736 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:10795736 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:10795736 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:10795736 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:10795736 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:10795736 | pubmed:month | Apr | lld:pubmed |
pubmed-article:10795736 | pubmed:issn | 1074-7613 | lld:pubmed |
pubmed-article:10795736 | pubmed:author | pubmed-author:RobelPP | lld:pubmed |
pubmed-article:10795736 | pubmed:author | pubmed-author:ItanoAA | lld:pubmed |
pubmed-article:10795736 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:10795736 | pubmed:volume | 12 | lld:pubmed |
pubmed-article:10795736 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:10795736 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:10795736 | pubmed:pagination | 383-9 | lld:pubmed |
pubmed-article:10795736 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
pubmed-article:10795736 | pubmed:meshHeading | pubmed-meshheading:10795736... | lld:pubmed |
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pubmed-article:10795736 | pubmed:meshHeading | pubmed-meshheading:10795736... | lld:pubmed |
pubmed-article:10795736 | pubmed:year | 2000 | lld:pubmed |
pubmed-article:10795736 | pubmed:articleTitle | Highly efficient selection of CD4 and CD8 lineage thymocytes supports an instructive model of lineage commitment. | lld:pubmed |
pubmed-article:10795736 | pubmed:affiliation | Department of Molecular and Cell Biology, University of California, Berkeley 94720, USA. | lld:pubmed |
pubmed-article:10795736 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:10795736 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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