pubmed-article:10795415 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:10795415 | lifeskim:mentions | umls-concept:C0025663 | lld:lifeskim |
pubmed-article:10795415 | lifeskim:mentions | umls-concept:C1511790 | lld:lifeskim |
pubmed-article:10795415 | lifeskim:mentions | umls-concept:C0699900 | lld:lifeskim |
pubmed-article:10795415 | lifeskim:mentions | umls-concept:C0243125 | lld:lifeskim |
pubmed-article:10795415 | lifeskim:mentions | umls-concept:C1514468 | lld:lifeskim |
pubmed-article:10795415 | lifeskim:mentions | umls-concept:C0078847 | lld:lifeskim |
pubmed-article:10795415 | lifeskim:mentions | umls-concept:C0439831 | lld:lifeskim |
pubmed-article:10795415 | lifeskim:mentions | umls-concept:C0667613 | lld:lifeskim |
pubmed-article:10795415 | pubmed:issue | 4 | lld:pubmed |
pubmed-article:10795415 | pubmed:dateCreated | 2000-5-11 | lld:pubmed |
pubmed-article:10795415 | pubmed:abstractText | Zopiclone (Zimovane) is a cyclopyrrolone compound which exhibits hypnotic and sedative effects while also exhibiting anticonvulsant and muscle relaxant activities. The detection and quantification of zopiclone is difficult. It has a high molecular weight compared to most other commonly used drugs, therapeutic levels are not high, and it is unstable in nucleophilic solvents. A degradation product of zopiclone, 2-amino-5-chloropyridine (ACP) together with a method for its detection using high-performance liquid chromatography with diode array detection has been described previously. An account is presented of a simple method for the detection of ACP using gas chromatography with mass selective detection (GC/MS) which will facilitate detection of zopiclone use as part of a routine screen. | lld:pubmed |
pubmed-article:10795415 | pubmed:language | eng | lld:pubmed |
pubmed-article:10795415 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:10795415 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:10795415 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:10795415 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:10795415 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:10795415 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:10795415 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:10795415 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:10795415 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:10795415 | pubmed:issn | 1355-0306 | lld:pubmed |
pubmed-article:10795415 | pubmed:author | pubmed-author:ForrestA RAR | lld:pubmed |
pubmed-article:10795415 | pubmed:author | pubmed-author:GallowayJ HJH | lld:pubmed |
pubmed-article:10795415 | pubmed:author | pubmed-author:MarshI DID | lld:pubmed |
pubmed-article:10795415 | pubmed:author | pubmed-author:NewtonC MCM | lld:pubmed |
pubmed-article:10795415 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:10795415 | pubmed:volume | 39 | lld:pubmed |
pubmed-article:10795415 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:10795415 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:10795415 | pubmed:pagination | 253-6 | lld:pubmed |
pubmed-article:10795415 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
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pubmed-article:10795415 | pubmed:articleTitle | A method for the rapid detection of the zopiclone degradation product 2-amino-5-chloropyridine. | lld:pubmed |
pubmed-article:10795415 | pubmed:affiliation | Department of Clinical Chemistry, Royal Hallamshire Hospital, Sheffield, United Kingdom. | lld:pubmed |
pubmed-article:10795415 | pubmed:publicationType | Journal Article | lld:pubmed |